Novel endothelial progenitor cells populations as biomarkers of damage and remission in systemic lupus erythematosus

• Published in: Arthritis research & therapy Vol. 26; no. 1; pp. 170 - 9
• Main Authors: Rafael-Vidal, Carlos, Martínez-Ramos, Sara, Malvar-Fernández, Beatriz, Altabás-González, Irene, Mouriño, Coral, Pazos-López, Pablo, Fraga-Bau, Arturo, Pego Reigosa, José María, García, Samuel
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 28.09.2024; BioMed Central; BMC
• Subjects: Adult; Biological markers; Biomarkers - metabolism; Damage; Development and progression; Diagnosis; Endothelial progenitor cells; Endothelial Progenitor Cells - metabolism; EPCs clusters; Epithelial cells; Female; Flow Cytometry - methods; Health aspects; Humans; Identification and classification; Immunological research; Leukocytes, Mononuclear - metabolism; Lupus Erythematosus, Systemic - blood; Lupus Erythematosus, Systemic - metabolism; Male; Middle Aged; Regression (Disease); Remission; Remission Induction; Systemic lupus erythematosus; Spain; Remission; Systemic lupus erythematosus; Damage; EPCs clusters; Endothelial progenitor cells

Endothelial progenitor cells (EPCs) are essential for maintenance of vascular homeostasis and stability, key processes in the pathogenesis of systemic lupus erythematosus (SLE). However, the role and phenotypic characterization of EPCs populations in SLE have not been completely elucidated. To ident...