Model-Informed Immunogenicity Assessment of Nivolumab as Monotherapy and in Combination with Ipilimumab - Zhao, Yue; Li, Li; Ma, Jessica; Roy, Amit; Bello, Akintunde; Sheng, Jennifer; Hamuro, Lora (The AAPS journal, 2025)
Keywords: Antineoplastic Combined Chemotherapy Protocols - administration & dosage; Antineoplastic Combined Chemotherapy Protocols - adverse effects; Antineoplastic Combined Chemotherapy Protocols - immunology; Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics; Biochemistry; Biomedical and Life Sciences; Biomedicine; Biotechnology; Carcinoma, Non-Small-Cell Lung - drug therapy; Carcinoma, Non-Small-Cell Lung - immunology; Carcinoma, Non-Small-Cell Lung - mortality; Comparative analysis; Female; Humans; Ipilimumab; Ipilimumab - administration & dosage; Ipilimumab - adverse effects; Ipilimumab - pharmacokinetics; Lung cancer, Non-small cell; Lung Neoplasms - drug therapy; Lung Neoplasms - immunology; Lung Neoplasms - mortality; Male; Melanoma; Melanoma - drug therapy; Melanoma - immunology; Melanoma - mortality; Models, Biological; Nivolumab - administration & dosage; Nivolumab - adverse effects; Nivolumab - immunology; Nivolumab - pharmacokinetics; Pharmacology/Toxicology; Pharmacy; Research Article; Population pharmacokinetics; Antidrug antibodies; Immunogenicity; Biologics; Ipilimumab; Nivolumab; Clinical outcomes