The statistical foundation of the reference population for semen analysis included in the sixth edition of the WHO manual: a critical reappraisal of the evidence

• Published in: Human reproduction (Oxford) Vol. 37; no. 10; pp. 2237 - 2245
• Main Authors: Paffoni, Alessio, Somigliana, Edgardo, Boeri, Luca, Viganò, Paola
• Format: Journal Article
• Language: English
• Published: Oxford University Press 30.09.2022
• Subjects: Opinion

Abstract In the most recent version of the ‘WHO Laboratory Manual For The Examination And Processing Of Human Semen’, the updated target population used to infer reference values included 3589 fertile subjects, representative of 12 countries and 5 continents, and 10 studies. We have critically evalu...