The High Resolutive Detection of TiO2 Nanoparticles in Human Corneocytes via TEM/NanoSIMS Correlation

• Published in: Applied sciences Vol. 13; no. 22; p. 12189
• Main Authors: Janin, Morgane, Delaune, Anthony, Gibouin, David, Delaroche, Fabien, Klaes, Benjamin, Etienne, Auriane, Cabin-Flaman, Armelle
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.11.2023
• Subjects: correlation; image registration; Nanoparticles; Polymerization; Scanning electron microscopy; Scientific imaging; SCP filter; SIMS; Skin; Software; Sunscreen; TEM; Titanium; X-rays; United Kingdom > UK; United States > US; Japan; Germany

Titanium dioxide (TiO2) nanoparticles (NPs) are the subject of numerous studies and controversies on the risks they could pose to the environment and human health. When in contact with biological tissues, NPs can sometimes be challenging to precisely localize within subcellular structures (typically...