Abemaciclib-associated Diarrhea: An Exploratory Analysis of Real-life Data

• Published in: Anticancer research Vol. 43; no. 3; pp. 1291 - 1299
• Main Authors: GEBBIA, VITTORIO, MARTORANA, FEDERICA, SANÒ, MARIA VITA, VALERIO, MARIA ROSARIA, GIOTTA, FRANCESCO, SPADA, MASSIMILIANO, PIAZZA, DARIO, CARUSO, MICHELE, VIGNERI, PAOLO
• Format: Journal Article
• Language: English
• Published: Greece 01.03.2023
• Subjects: Aged; Aminopyridines - adverse effects; Benzimidazoles - adverse effects; Breast Neoplasms - drug therapy; Diarrhea - chemically induced; Female; Humans; Abemaciclib; diet; comorbidities; diarrhea; age; polypharmacy

Abemaciclib is a cyclin-dependent kinase 4/6 inhibitor approved in combination with endocrine therapy for treating hormone receptor-positive and human epidermal growth factor receptor 2-negative early and advanced breast cancer patients. The safety profile of abemaciclib is characterized by frequent...