PTS 50: Past, Present and Future, or Diauxie Revisited

• Published in: Journal of molecular microbiology and biotechnology Vol. 25; no. 2-3; pp. 79 - 93
• Main Author: Lengeler, Joseph W
• Format: Journal Article
• Language: English
• Published: Switzerland S. Karger AG 01.01.2015
• Subjects: Bacteria; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Biological Transport; Carbohydrates; Catabolite Repression; Cell differentiation; Gram-Negative Bacteria - genetics; Gram-Negative Bacteria - metabolism; Gram-Positive Bacteria - genetics; Gram-Positive Bacteria - metabolism; History, 20th Century; History, 21st Century; Phosphoenolpyruvate - metabolism; Phosphoenolpyruvate Sugar Phosphotransferase System - history; Phosphoenolpyruvate Sugar Phosphotransferase System - metabolism; Phosphorylation

PAST: The title 'PTS 50 or The PTS after 50 years' relies on the first description in 1964 of the phosphoenolpyruvate-dependent carbohydrate:phosphotransferase system (PTS) by Kundig, Gosh and Roseman [Proc Natl Acad Sci USA 1964;52:1067-1074]. The system comprised proteins named Enzyme I,...