Call to action for clinicians in the South-East Asian regions on primary prevention of diabetes in people with prediabetes- A consensus statement

• Published in: Diabetes research and clinical practice Vol. 221; p. 111997
• Main Authors: Ramachandran, Ambady, Nanditha, Arun, Tuomilehto, Jaakko, Gabriel, Rafael, Saboo, Banshi, Mohan, Viswanathan, Chawla, Manoj, Chawla, Purvi, Raghavan, Arun, Gupta, Amit, Joshi, Shashank, Agarwal, Sanjay, Misra, Anoop, Sahay, Rakesh, Tiwaskar, Mangesh H., Azad Khan, A.K., Arvind, S.R., Viswanathan, Vijay, Das, Ashok Kumar, Makkar, Brij Mohan, Kowlessur, Sudhirsen, Yajnik, Chittaranjan S., Sriram, Usha, Seshadri, Krishna G., Susairaj, Priscilla, Satheesh, Krishnamoorthy, Duncan, Bruce B., Aschner, Pablo, Barengo, Noel C, Schwarz, Peter E.H., Ceriello, Antonio
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.03.2025
• Subjects: Asia, Southeastern - epidemiology; Diabetes Mellitus, Type 2 - epidemiology; Diabetes Mellitus, Type 2 - prevention & control; Humans; India - epidemiology; Prediabetic State - epidemiology; Prediabetic State - prevention & control; Primary Prevention - methods; Asia, Southeastern; India
• DOI: 10.1016/j.diabres.2025.111997
• ISSN: 0168-8227; 1872-8227

Primary prevention of diabetes still remains as an unmet challenge in a real world setting. While, translational programmes have been successful in the developed nations, the prevailing social and economic inequities in the low and middle income countries, fail to integrate diabetes prevention into their public health systems. The resulting exponential increase in the prevalence of diabetes and the cost of treatment has put primary prevention in the back seat. As a call to action, an expert group was formed to lay down practical guidelines for clinicians in the South East Asian regions to implement primary prevention programmes at an individual or at a community level. The guideline was developed based on the outcomes of the evidence based prevention programmes conducted in India. This decentralised self-guided approach for primary prevention of diabetes follows a three step implementation process of screening, diagnosis of intermediate hyperglycaemia and design and delivery of personalized interventions. Recommendations provided on dietary intake and physical activity can be tailored by the clinician to suit individual needs. Initiation of pharmacological treatment to achieve desired targets has also been addressed. A personalised approach by the clinician may be effective and offer a sustainable solution to curb the rising epidemic.