Stoichiometry of Rtt109 complexes with Vps75 and histones H3-H4

• Published in: Life science alliance Vol. 3; no. 11; p. e202000771
• Main Authors: Akhavantabib, Noushin, Krzizike, Daniel D, Neumann, Victoria, D’Arcy, Sheena
• Format: Journal Article
• Language: English
• Published: Life Science Alliance LLC 01.11.2020

Histone acetylation is one of many posttranslational modifications that affect nucleosome accessibility. Vps75 is a histone chaperone that stimulates Rtt109 acetyltransferase activity toward histones H3-H4 in yeast. In this study, we use sedimentation velocity and light scattering to characterize va...