Regional anesthetic techniques are an alternative to general anesthesia for infants with Pompe's disease

• Published in: Pediatric anesthesia Vol. 17; no. 7; pp. 697 - 702
• Main Authors: WALKER, ROBERT W.M., BRIGGS, GERAINT, BRUCE, JAMES, FLETCHER, JOAN, WRAITH, E.D.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.07.2007
• Subjects: Anesthesia, Conduction; Anesthesia, General; Anesthetics, Combined; Biopsy; Catheters, Indwelling; caudal epidural block; Child, Preschool; Conscious Sedation; Female; Femoral Nerve; femoral nerve block; Glycogen - metabolism; glycogen storage disease type II; Glycogen Storage Disease Type II - diagnosis; Glycogen Storage Disease Type II - pathology; Humans; hypertrophic cardiomyopathy; Infant; Lidocaine; Male; Muscle, Skeletal - metabolism; Muscle, Skeletal - pathology; Nerve Block; Pompe's disease; Prilocaine; regional anesthesia; Treatment Outcome

Summary Pompe's disease or glycogen storage disease type II is a genetic disorder affecting skeletal and cardiac muscle. The infantile form is associated with gross hypertrophic cardiomegaly and death in the early years. General anesthesia is associated with potential major morbidity in these p...