Recent Advances in Dynamic Monitoring of Drug Release of Nanoparticle Using Förster Resonance Energy Transfer and Fluorescence Lifetime Imaging

• Published in: Journal of the Chinese Chemical Society (Taipei) Vol. 58; no. 6; pp. 798 - 804
• Main Authors: Cheng, Shih-Hsun, Chen, Nai-Tzu, Wu, Chia-Yan, Chung, Chao-Yu, Hwu, Yeukuang, Mou, Chung-Yuan, Yang, Chung-Shi, Lo, Leu-Wei
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 01.10.2011; WILEY‐VCH Verlag
• Subjects: Drug release dynamics; FLIM; FRET; Nanoparticle

In this review, we summarized the recent advances in dynamic monitoring of drug release of nanoparticle using FRET and FLIM. Using FRET to understanding the dynamics of drug released from its nanocarrier within intracellular milieu provides high sensitivity and temporal information of the releasing...