Erythrocyte and reticulocyte indices in the assessment of erythropoiesis activity and iron availability

• Published in: International journal of laboratory hematology Vol. 35; no. 2; pp. 144 - 149
• Main Authors: Urrechaga, E., Borque, L., Escanero, J. F.
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.04.2013
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Iron-Deficiency - diagnosis; Automation; Clinical Chemistry Tests - methods; Dialysis; erythropoiesis; Erythropoiesis - physiology; Female; Flow Cytometry; hemodialysis; Humans; hypochromic erythrocyte; Iron - blood; Iron - deficiency; iron availability; Male; Middle Aged; Reference Standards; Renal Insufficiency, Chronic - diagnosis; Reticulocyte hemoglobin content; ROC Curve; Sensitivity and Specificity

Summary Introduction Consequence of the imbalance between the erythroid marrow iron requirements and the actual supply is a reduction in red cell hemoglobin content, which causes hypochromic mature red cells and reticulocytes. Sysmex XE 5000 analyzer (Sysmex Corporation, Kobe, Japan) reports reticul...