Differential expression of MAP3K7 and TROPONIN C proteins and related perturbations in renal amyloidosis

• Published in: Expert review of proteomics Vol. 17; no. 9; p. 685
• Main Authors: Gupta, Nimisha, Sahar, Tahreem, Khullar, Dinesh, Jain, S K, Wajid, Saima
• Format: Journal Article
• Language: English
• Published: England 01.09.2020
• Subjects: MALDI-TOF MS; two-dimensional electrophoresis; bio-layer Interferometry; Proteomics; renal amyloidosis

Renal amyloidosis (RA) is a rare protein misfolding disorder that prompts progressive renal insufficiency. This study aimed to decipher proteomic changes in human sera to understand the pathophysiology and molecular mechanisms underlying the disease development, hence assisting in the diagnosis of R...