Effects of Botulinum Toxin A Injection on Ambulation Capacity in Patients with Cerebral Palsy
Purpose: The purpose of the study is to assess the change in their ambulatory capacity and spasticity in children with cerebral palsy (CP) who received botulinum toxin A (BoNT-A) injection and underwent rehabilitation therapy. Methods: Thirty patients with CP, 3-13 years who had varied functional le...
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| Published in | Developmental neurorehabilitation Vol. 22; no. 4; pp. 288 - 291 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Taylor & Francis
19.05.2019
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| Subjects | |
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| Abstract | Purpose: The purpose of the study is to assess the change in their ambulatory capacity and spasticity in children with cerebral palsy (CP) who received botulinum toxin A (BoNT-A) injection and underwent rehabilitation therapy.
Methods: Thirty patients with CP, 3-13 years who had varied functional levels and lower extremity spasticity, were randomized in two groups. In Group 1(n = 15), BoNT-A was administered to the affected extremity and underwent rehabilitation. In Group 2 (n = 15), the patients underwent only rehabilitation protocol. The Visual Analogue Scale (VAS), Tardieu Scale (TS), Gross Motor Function Classification System (GMFCS), Selective Motor Control, and Goal Attainment Scale were evaluated 4 and 12 weeks after baseline.
Results: The mean scores of the TS (p < 0.001) GMFCS, GAS, and VAS (p < 0.05) significantly improved in Group 1.
Conclusion: We think that implementation of rehabilitation protocols with BoNT-A injection is superior to alone rehabilitation therapy and increasing ambulatory capacity in patients with CP. |
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| AbstractList | Purpose: The purpose of the study is to assess the change in their ambulatory capacity and spasticity in children with cerebral palsy (CP) who received botulinum toxin A (BoNT-A) injection and underwent rehabilitation therapy.
Methods: Thirty patients with CP, 3-13 years who had varied functional levels and lower extremity spasticity, were randomized in two groups. In Group 1(n = 15), BoNT-A was administered to the affected extremity and underwent rehabilitation. In Group 2 (n = 15), the patients underwent only rehabilitation protocol. The Visual Analogue Scale (VAS), Tardieu Scale (TS), Gross Motor Function Classification System (GMFCS), Selective Motor Control, and Goal Attainment Scale were evaluated 4 and 12 weeks after baseline.
Results: The mean scores of the TS (p < 0.001) GMFCS, GAS, and VAS (p < 0.05) significantly improved in Group 1.
Conclusion: We think that implementation of rehabilitation protocols with BoNT-A injection is superior to alone rehabilitation therapy and increasing ambulatory capacity in patients with CP. PURPOSEThe purpose of the study is to assess the change in their ambulatory capacity and spasticity in children with cerebral palsy (CP) who received botulinum toxin A (BoNT-A) injection and underwent rehabilitation therapy.METHODSThirty patients with CP, 3-13 years who had varied functional levels and lower extremity spasticity, were randomized in two groups. In Group 1(n = 15), BoNT-A was administered to the affected extremity and underwent rehabilitation. In Group 2 (n = 15), the patients underwent only rehabilitation protocol. The Visual Analogue Scale (VAS), Tardieu Scale (TS), Gross Motor Function Classification System (GMFCS), Selective Motor Control, and Goal Attainment Scale were evaluated 4 and 12 weeks after baseline.RESULTSThe mean scores of the TS (p < 0.001) GMFCS, GAS, and VAS (p < 0.05) significantly improved in Group 1.CONCLUSIONWe think that implementation of rehabilitation protocols with BoNT-A injection is superior to alone rehabilitation therapy and increasing ambulatory capacity in patients with CP. The purpose of the study is to assess the change in their ambulatory capacity and spasticity in children with cerebral palsy (CP) who received botulinum toxin A (BoNT-A) injection and underwent rehabilitation therapy. Thirty patients with CP, 3-13 years who had varied functional levels and lower extremity spasticity, were randomized in two groups. In Group 1(n = 15), BoNT-A was administered to the affected extremity and underwent rehabilitation. In Group 2 (n = 15), the patients underwent only rehabilitation protocol. The Visual Analogue Scale (VAS), Tardieu Scale (TS), Gross Motor Function Classification System (GMFCS), Selective Motor Control, and Goal Attainment Scale were evaluated 4 and 12 weeks after baseline. The mean scores of the TS (p < 0.001) GMFCS, GAS, and VAS (p < 0.05) significantly improved in Group 1. We think that implementation of rehabilitation protocols with BoNT-A injection is superior to alone rehabilitation therapy and increasing ambulatory capacity in patients with CP. |
| Author | Şenel, Kazım Çağlar Okur, Sibel Uğur, Mahir |
| Author_xml | – sequence: 1 givenname: Sibel orcidid: 0000-0002-4015-5977 surname: Çağlar Okur fullname: Çağlar Okur, Sibel email: sibelcaglarokur@gmail.com organization: Health Science University, Bakırköy Dr Sadi Konuk Training and Research Hospital, Physical Therapy and Rehabilitation Clinic – sequence: 2 givenname: Mahir orcidid: 0000-0003-1522-9118 surname: Uğur fullname: Uğur, Mahir organization: Atatürk University School of Medicine, Physical Therapy and Rehabilitation Clinic – sequence: 3 givenname: Kazım orcidid: 0000-0002-2722-4405 surname: Şenel fullname: Şenel, Kazım organization: Atatürk University School of Medicine, Physical Therapy and Rehabilitation Clinic |
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| Title | Effects of Botulinum Toxin A Injection on Ambulation Capacity in Patients with Cerebral Palsy |
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