Increased levels of low density neutrophils (LDNs) in myocardial infarction

• Published in: Acta cardiologica Vol. 78; no. 1; p. 47
• Main Authors: Yiu, Jacquelina Y T, Hally, Kathryn E, Larsen, Peter D, Holley, Ana S
• Format: Journal Article
• Language: English
• Published: England 02.01.2023
• Subjects: Humans; Leukocytes, Mononuclear; Myocardial Infarction - diagnosis; Neutrophils - pathology; Neutrophils - physiology; Low-density neutrophils; immunophenotyping; inflammation; neutrophil subsets; myocardial infarction

Recent evidence suggests that neutrophils are highly plastic cells that can display heterogeneous phenotypes. Low-density neutrophils (LDNs) have been described in many inflammatory conditions, and are thought to represent an immature, hyperactivated subtype of neutrophils. Neutrophils are significa...