Prevalence of Mycoplasma genitalium and other sexually transmitted infections causing urethritis among high-risk heterosexual male patients in Estonia

• Published in: Infectious diseases (London, England) Vol. 50; no. 2; pp. 133 - 139
• Main Authors: Tjagur, Stanislav, Mändar, Reet, Punab, Margus
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 01.02.2018
• Subjects: Adolescent; Adult; Chlamydia trachomatis; Chlamydia trachomatis - physiology; Estonia - epidemiology; Heterosexuality; Humans; inflammation; Male; Middle Aged; Mycoplasma genitalium - physiology; Mycoplasma genitalium; Neisseria gonorrhoeae; Mycoplasma Infections - complications; Mycoplasma Infections - epidemiology; Mycoplasma Infections - microbiology; Neisseria gonorrhoeae - physiology; Prevalence; risk behaviour; Risk Factors; Sexually Transmitted Diseases - complications; Sexually Transmitted Diseases - epidemiology; Sexually Transmitted Diseases - microbiology; sexually transmitted infections; Trichomonas vaginalis; Trichomonas vaginalis - physiology; urethritis; Urethritis - epidemiology; Urethritis - etiology; Urethritis - microbiology; Young Adult; sexually transmitted infections; Trichomonas vaginalis; Mycoplasma genitalium; Neisseria gonorrhoeae; inflammation; risk behaviour; urethritis; Chlamydia trachomatis; male
• DOI: 10.1080/23744235.2017.1366044
• ISSN: 2374-4235

Background: We aimed to evaluate the prevalence of sexually transmitted infections (STI, including Mycoplasma genitalium, Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis) among high-risk heterosexual male patients and to clarify their potency to cause complaints and inflammation. Methods: The study group included 825 men (18.0-49.5 y) consulting andrologist at Tartu University Hospital (Estonia) due to subjectively perceived risk of STI. Patients completed STI risk behaviour questionnaire. First voided urine was analysed for white blood cells and STIs. Results: In total 193 (23.4%) patients were positive for one or multiple STI. The prevalence of C. trachomatis, M. genitalium, N. gonorrhoeae, T. vaginalis and combined STI was 14.3%, 4.4%, 2.7%, 0.7% and 1.3%, respectively. N. gonorrhoeae had the highest potency to generate inflammatory reaction in first voided urine (100%) followed by C. trachomatis (72.0%), M. genitalium (63.9%) and T. vaginalis (33.3%). N. gonorrhoeae and T. vaginalis caused the highest mean number of complaints while half of T. vaginalis cases and nearly fifth of M. genitalium and C. trachomatis cases were asymptomatic. Conclusions: C. trachomatis has the highest prevalence among Estonian high-risk men but M. genitalium holds an important second place. Prevalence of combined STIs is low. N. gonorrhoeae has the highest potency to generate urethral inflammation followed by C. trachomatis and M. genitalium. The highest number of complaints is also associated with N. gonorrhoeae while half of T. vaginalis cases and nearly a fifth of M. genitalium and C. trachomatis cases are asymptomatic.