Efficacy of supplemental MCT oil on seizure reduction of adult drug-resistant epilepsy - a single-center open-label pilot study

• Published in: Nutritional neuroscience Vol. 26; no. 6; pp. 535 - 539
• Main Authors: Rasmussen, Emmaline, Patel, Vimal, Tideman, Samuel, Frech, Robert, Frigerio, Roberta, Narayanan, Jaishree
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 03.06.2023
• Subjects: Adult; Diet, Ketogenic - adverse effects; dietary supplements; Drug resistant epilepsy; Drug Resistant Epilepsy - drug therapy; Humans; intractable epilepsy; Ketones; ketosis; medium chain triglycerides; Pilot Projects; seizures; Seizures - drug therapy; Seizures - prevention & control; standard of care; Triglycerides; ketosis; Drug resistant epilepsy; dietary supplements; seizures; standard of care; intractable epilepsy; ketones; medium chain triglycerides

We set out to determine whether adding medium chain triglyceride (MCT) oil as a dietary supplement to standard diet in adult subjects with intractable epilepsy in a U.S. neurology clinical practice was associated with a reduction in number of seizures. We secondarily aimed to determine whether subje...