Baicalein inhibits cell development, metastasis and EMT and induces apoptosis by regulating ERK signaling pathway in osteosarcoma

• Published in: Journal of receptors and signal transduction Vol. 40; no. 1; p. 49
• Main Authors: Lin, Hang, Hao, Yi, Wan, Xiaoqing, He, Jun, Tong, Yongjun
• Format: Journal Article
• Language: English
• Published: England 02.01.2020
• Subjects: epithelial mesenchymal transition (EMT); Baicalein; apoptosis; ERK signaling pathway; osteosarcoma

Osteosarcoma is a highly malignant primary tumor. Baicalein has broad-spectrum anti-tumor effects. This study aimed to study the specific molecular regulatory mechanism of baicalein in anti-osteosarcoma and the possible regulatory signaling network involved. In vitro experiment, MG-63 cells treated...