Recent advances of exosomes in immune modulation and autoimmune diseases

Exosomes are small membrane-bound vesicles (30-100 nm) that are secreted by different types of cells and they have been well documented to resemble saucers or flattened spheres under the electron microscope. Recently, evidence indicates that exosomes play important roles in the immune modulation and...

Full description

Saved in:
Bibliographic Details
Published inAutoimmunity (Chur, Switzerland) Vol. 49; no. 6; pp. 357 - 365
Main Authors Tan, Lina, Wu, Haijing, Liu, Ying, Zhao, Ming, Li, Duo, Lu, Qianjin
Format Journal Article
LanguageEnglish
Published England Taylor & Francis 01.09.2016
Subjects
Animals
Autoimmune Diseases - drug therapy
Autoimmune Diseases - etiology
Autoimmune Diseases - metabolism
Autoimmunity
Biological Transport
Biomarkers
Exosome
Exosomes - metabolism
Humans
Immune System - cytology
Immune System - immunology
Immune System - metabolism
Immunomodulation
microRNA
MicroRNAs - genetics
MicroRNAs - metabolism
Molecular Targeted Therapy
rheumatoid arthritis
Sjogren's syndrome
systemic lupus erythematosus
microRNA
systemic lupus erythematosus
Sjogren’s syndrome
Exosome
rheumatoid arthritis
Online AccessGet full text

Cover

Abstract Exosomes are small membrane-bound vesicles (30-100 nm) that are secreted by different types of cells and they have been well documented to resemble saucers or flattened spheres under the electron microscope. Recently, evidence indicates that exosomes play important roles in the immune modulation and are associated with the immune pathogenesis of autoimmune diseases, including rheumatoid arthritis (RA), Sjogren's syndrome (SS) and systemic lupus erythematosus (SLE). In this review, we will summarize current research advances of exosomes in immunoregulation, pathogenesis, diagnosis and therapeutics of autoimmune diseases.
AbstractList Exosomes are small membrane-bound vesicles (30-100 nm) that are secreted by different types of cells and they have been well documented to resemble saucers or flattened spheres under the electron microscope. Recently, evidence indicates that exosomes play important roles in the immune modulation and are associated with the immune pathogenesis of autoimmune diseases, including rheumatoid arthritis (RA), Sjogren's syndrome (SS) and systemic lupus erythematosus (SLE). In this review, we will summarize current research advances of exosomes in immunoregulation, pathogenesis, diagnosis and therapeutics of autoimmune diseases.Exosomes are small membrane-bound vesicles (30-100 nm) that are secreted by different types of cells and they have been well documented to resemble saucers or flattened spheres under the electron microscope. Recently, evidence indicates that exosomes play important roles in the immune modulation and are associated with the immune pathogenesis of autoimmune diseases, including rheumatoid arthritis (RA), Sjogren's syndrome (SS) and systemic lupus erythematosus (SLE). In this review, we will summarize current research advances of exosomes in immunoregulation, pathogenesis, diagnosis and therapeutics of autoimmune diseases.
Exosomes are small membrane-bound vesicles (30-100 nm) that are secreted by different types of cells and they have been well documented to resemble saucers or flattened spheres under the electron microscope. Recently, evidence indicates that exosomes play important roles in the immune modulation and are associated with the immune pathogenesis of autoimmune diseases, including rheumatoid arthritis (RA), Sjogren's syndrome (SS) and systemic lupus erythematosus (SLE). In this review, we will summarize current research advances of exosomes in immunoregulation, pathogenesis, diagnosis and therapeutics of autoimmune diseases.
Author Liu, Ying
Lu, Qianjin
Wu, Haijing
Zhao, Ming
Tan, Lina
Li, Duo
Author_xml – sequence: 1
  givenname: Lina
  surname: Tan
  fullname: Tan, Lina
  organization: Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics
– sequence: 2
  givenname: Haijing
  surname: Wu
  fullname: Wu, Haijing
  organization: Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics
– sequence: 3
  givenname: Ying
  surname: Liu
  fullname: Liu, Ying
  organization: Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics
– sequence: 4
  givenname: Ming
  surname: Zhao
  fullname: Zhao, Ming
  organization: Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics
– sequence: 5
  givenname: Duo
  surname: Li
  fullname: Li, Duo
  organization: Department of Pathology, Second Xiangya Hospital, Central South University
– sequence: 6
  givenname: Qianjin
  surname: Lu
  fullname: Lu, Qianjin
  email: qianlu5860@gmail.com
  organization: Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics
BackLink https://www.ncbi.nlm.nih.gov/pubmed/27259064$$D View this record in MEDLINE/PubMed
BookMark eNqFkctOwzAQRS0Eog_4BFCWbFLsJH5EbEAVUKRKSKgLdpZrTySjxC52AvTvSWi7YQGrGWnOncedCTp23gFCFwTPCBb4GouSsDIvZhkmbEZISQrOj9CYMMxTUWSvx2g8MOkAjdAkxjeMccZZcYpGGc9oiVkxRosX0ODaRJkP5TTExFcJfPnomz63LrFN0zlIGm-6WrXWu0Q5k6iu9fuKsRFUhHiGTipVRzjfxylaPdyv5ot0-fz4NL9bpjpnrE21zitNKAW2FmW_OeSQKUOVKYtCgyiAcyoIzYzh2GBTGW6U7petKFVinedTdLVruwn-vYPYysZGDXWtHPguSiIyxkpBygG93KPdugEjN8E2Kmzl4fgeuNkBOvgYA1RS2_bnyDYoW0uC5WC1PFgtB6vl3upeTX-pDwP-093udNZVPjTq04fayFZtax-q0D_BRpn_3eIbe_iVdQ
CitedBy_id crossref_primary_10_3390_biology10070579
crossref_primary_10_1002_INMD_20240049
crossref_primary_10_1021_acs_molpharmaceut_2c00542
crossref_primary_10_1002_jcp_27014
crossref_primary_10_3389_fmolb_2022_846650
crossref_primary_10_1007_s00216_018_1548_y
crossref_primary_10_1016_j_mce_2020_110756
crossref_primary_10_1177_1535370220934736
crossref_primary_10_3389_fimmu_2019_01561
crossref_primary_10_1292_jvms_19_0643
crossref_primary_10_1039_D1NA00330E
crossref_primary_10_1111_brv_12608
crossref_primary_10_1007_s10067_021_05651_5
crossref_primary_10_1007_s12026_019_09088_6
crossref_primary_10_1080_20013078_2017_1400370
crossref_primary_10_3390_biom10121641
crossref_primary_10_3389_fimmu_2018_00137
crossref_primary_10_1038_leu_2017_91
crossref_primary_10_1373_clinchem_2018_291963
crossref_primary_10_3389_fcell_2020_00202
crossref_primary_10_3390_cells10112989
crossref_primary_10_36868_medmater_2023_03_01_013
crossref_primary_10_1155_2019_3256060
crossref_primary_10_1080_08820139_2022_2090261
crossref_primary_10_1007_s11010_021_04248_5
crossref_primary_10_2174_1381612826666200523174108
crossref_primary_10_3390_ani11082466
crossref_primary_10_3390_vaccines11030687
crossref_primary_10_3389_fimmu_2020_01051
crossref_primary_10_1016_j_clim_2019_04_010
crossref_primary_10_2174_1574888X17666220330005937
crossref_primary_10_1016_j_mtbio_2023_100556
crossref_primary_10_1002_jcp_27934
crossref_primary_10_1080_08916934_2018_1442441
crossref_primary_10_3389_fimmu_2021_757674
crossref_primary_10_1039_C9BM01761E
crossref_primary_10_1016_j_jneuroim_2021_577640
crossref_primary_10_1186_s13578_020_00424_0
crossref_primary_10_2147_IJN_S372042
crossref_primary_10_1002_elps_201800526
crossref_primary_10_3389_fimmu_2019_01464
crossref_primary_10_3390_ijms22115456
crossref_primary_10_1038_s41598_019_52073_0
crossref_primary_10_1016_j_intimp_2021_108409
crossref_primary_10_3389_fonc_2022_940056
crossref_primary_10_1186_s13287_021_02541_0
crossref_primary_10_3389_fphar_2022_930638
crossref_primary_10_1210_en_2018_00649
crossref_primary_10_1002_path_5061
crossref_primary_10_1038_s41419_020_02803_4
crossref_primary_10_3390_ijms241210162
crossref_primary_10_1111_odi_13795
crossref_primary_10_36290_der_2022_001
crossref_primary_10_29252_koomesh_22_2_209
crossref_primary_10_1093_ibd_izab132
crossref_primary_10_1186_s11658_021_00280_x
crossref_primary_10_1016_j_talanta_2020_120851
crossref_primary_10_1080_14737159_2021_1933946
crossref_primary_10_1016_j_cytox_2022_100066
crossref_primary_10_3389_fimmu_2024_1388574
crossref_primary_10_3390_ijms21072631
crossref_primary_10_3390_ijms22042165
crossref_primary_10_1016_j_lfs_2025_123451
crossref_primary_10_1016_j_cellimm_2020_104219
crossref_primary_10_1007_s12035_019_01797_1
crossref_primary_10_1007_s12079_021_00646_y
crossref_primary_10_3389_fonc_2023_1131435
crossref_primary_10_1007_s00018_021_04020_4
crossref_primary_10_1186_s12950_024_00381_2
crossref_primary_10_1007_s00251_020_01180_8
crossref_primary_10_1186_s12967_020_02609_0
crossref_primary_10_1186_s12967_022_03487_4
crossref_primary_10_1038_s12276_022_00751_x
crossref_primary_10_1016_j_biochi_2023_05_010
crossref_primary_10_3389_fimmu_2022_939433
crossref_primary_10_1002_adsr_202400002
crossref_primary_10_3390_ijms23115877
crossref_primary_10_1093_rheumatology_keaa163
crossref_primary_10_3389_fimmu_2020_593348
crossref_primary_10_7717_peerj_14579
crossref_primary_10_1016_j_canlet_2019_03_021
crossref_primary_10_1111_cei_12974
crossref_primary_10_3390_cells8020154
crossref_primary_10_1021_acsinfecdis_3c00348
crossref_primary_10_1093_cei_uxae101
crossref_primary_10_1016_j_clim_2019_06_006
crossref_primary_10_1080_08820139_2024_2440772
crossref_primary_10_3390_ijms22157763
crossref_primary_10_3389_fcell_2022_835566
crossref_primary_10_3390_cells9051211
crossref_primary_10_1016_j_intimp_2022_109303
crossref_primary_10_1038_s41598_022_10738_3
crossref_primary_10_1016_j_bbrc_2020_03_088
crossref_primary_10_1016_j_taap_2021_115559
crossref_primary_10_3389_frph_2023_1130849
crossref_primary_10_1016_j_apsb_2022_08_020
crossref_primary_10_1002_adtp_201800032
crossref_primary_10_12677_ACM_2022_12121725
crossref_primary_10_1080_14767058_2018_1432037
crossref_primary_10_1007_s11051_025_06232_2
crossref_primary_10_2139_ssrn_4098857
crossref_primary_10_1080_08916934_2022_2067984
crossref_primary_10_3389_fimmu_2020_01506
crossref_primary_10_1080_1744666X_2018_1519396
crossref_primary_10_1007_s11481_019_09875_w
crossref_primary_10_1002_biof_1497
crossref_primary_10_3389_fimmu_2020_01509
crossref_primary_10_1038_s41386_020_0622_2
crossref_primary_10_14336_AD_2021_0513
crossref_primary_10_1016_j_vetimm_2018_12_003
crossref_primary_10_3389_fimmu_2022_1102405
crossref_primary_10_1016_j_exer_2021_108626
crossref_primary_10_1080_08916934_2017_1416468
crossref_primary_10_1007_s40618_017_0716_9
crossref_primary_10_1016_j_jaut_2024_103235
crossref_primary_10_5808_GI_2018_16_4_e19
crossref_primary_10_1155_2019_4312016
crossref_primary_10_1016_j_autrev_2020_102664
crossref_primary_10_3389_fimmu_2021_630112
crossref_primary_10_3390_ijms20205183
Cites_doi 10.1016/j.jconrel.2011.11.021
10.4049/jimmunol.181.2.1519
10.1002/art.22276
10.1111/j.1600-0854.2008.00734.x
10.1083/jcb.147.3.599
10.4049/jimmunol.0803477
10.1182/blood-2005-01-0220
10.1016/j.molimm.2007.11.021
10.1016/j.cell.2008.12.027
10.1007/s13277-013-0658-6
10.1016/j.clim.2006.07.007
10.1136/bmj.h5079
10.1038/ncomms1285
10.1007/978-1-59745-395-0_28
10.1177/0961203309358187
10.1016/j.semcancer.2014.05.003
10.1073/pnas.1209414109
10.1111/j.1600-0854.2009.00963.x
10.1073/pnas.0403453101
10.3109/08916934.2014.921811
10.1038/ncomms3980
10.1126/stke.16pe8
10.1111/j.1537-2995.2010.02909.x
10.2174/22115366113029990012
10.1007/s10238-013-0271-4
10.1126/science.281.5373.96
10.1016/j.pain.2014.04.029
10.1093/ndt/gfv128
10.1007/s12032-014-0148-8
10.3389/fimmu.2014.00555
10.1038/ki.2008.206
10.1002/eji.201242909
10.1111/j.1600-0897.2006.00435.x
10.1016/j.jaci.2013.04.048
10.1002/art.27501
10.4049/jimmunol.174.10.6440
10.1096/fj.03-1094fje
10.4049/jimmunol.172.4.2126
10.1371/journal.pone.0008577
10.1016/j.clinthera.2014.04.019
10.3390/s120303359
10.1016/j.nano.2014.03.014
10.1073/pnas.0914843107
10.1038/icb.2010.64
10.3389/fimmu.2014.00144
10.1182/blood-2011-08-374793
10.1073/pnas.1311145110
10.1016/j.canlet.2013.06.013
10.1016/j.ymthe.2005.09.015
10.1016/j.bbrc.2013.07.044
10.1002/eji.200838374
10.1038/ncb1929
10.1034/j.1600-0854.2002.30502.x
10.3109/08916934.2014.915955
10.1186/1479-5876-9-86
10.1016/j.clinbiochem.2013.10.020
10.1111/sji.12247
10.2337/db13-0859
10.1177/0961203310389841
10.1111/j.1365-2362.2010.02342.x
10.1002/hep.25873
10.1371/journal.pone.0138618
10.1016/j.bcmd.2005.05.002
10.1038/cr.2011.196
10.1111/imr.12059
10.1186/1476-4598-10-117
10.1371/journal.pone.0073798
10.1016/j.immuni.2014.07.001
10.3389/fimmu.2014.00043
10.2217/bmm.13.63
10.1111/imr.12013
10.1038/nrrheum.2014.19
10.1186/1757-2215-7-14
10.4161/rna.7.5.13216
10.1593/neo.122010
10.1182/blood-2011-02-338004
10.1038/nbt.1807
10.1007/s00262-003-0472-x
10.4049/jimmunol.177.7.4481
10.14791/btrt.2014.2.1.1
10.1016/j.immuni.2014.05.019
10.1371/journal.pone.0110383
10.1111/j.1365-2567.2005.02245.x
10.1038/ni854
10.1016/j.chom.2012.08.010
10.1074/jbc.M702277200
10.1084/jem.183.3.1161
10.1158/0008-5472.CAN-09-3276
10.1155/2012/573528
10.1371/journal.pntd.0002185
10.1007/s10059-013-0154-2
10.4049/jimmunol.179.3.1969
10.1038/ki.2010.106
10.1111/boc.201400081
10.4049/jimmunol.179.4.2242
10.1016/j.gde.2014.03.006
10.1002/art.21005
10.1038/nri2567
10.1016/j.bcp.2011.12.037
10.1111/j.1601-0825.2009.01604.x
10.3402/jev.v4.27066
ContentType Journal Article
Copyright 2016 Informa UK Limited, trading as Taylor & Francis Group. 2016
Copyright_xml – notice: 2016 Informa UK Limited, trading as Taylor & Francis Group. 2016
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
DOI 10.1080/08916934.2016.1191477
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
DatabaseTitleList MEDLINE - Academic
MEDLINE
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Biology
EISSN 1607-842X
EndPage 365
ExternalDocumentID 27259064
10_1080_08916934_2016_1191477
1191477
Genre Review Article
Journal Article
Review
GroupedDBID ---
00X
03L
0YH
23N
36B
4.4
5GY
AALUX
AAMIU
AAPUL
AAQRR
ABBKH
ABDBF
ABEIZ
ABJNI
ABLIJ
ABLKL
ABUPF
ABWVI
ABXYU
ACENM
ACGEJ
ACGFS
ACUHS
ADCVX
ADRBQ
ADXPE
ADYSH
AECIN
AENEX
AEOZL
AFKVX
AFRVT
AGDLA
AGFJD
AGRBW
AGYJP
AIJEM
AJWEG
AKBVH
ALMA_UNASSIGNED_HOLDINGS
ALQZU
ALYBC
AMDAE
BABNJ
BLEHA
BOHLJ
CCCUG
CS3
DKSSO
EAP
EBC
EBD
EBS
EJD
EMB
EMK
EMOBN
EPL
ESX
F5P
H13
HZ~
KRBQP
KSSTO
KWAYT
KYCEM
M4Z
O9-
P2P
RNANH
RVRKI
SV3
TBQAZ
TDBHL
TERGH
TFDNU
TFL
TFW
TUROJ
TUS
UEQFS
V1S
~1N
AAGDL
AAYXX
CITATION
53G
5VS
AALIY
AAORF
AAPXX
ABWCV
ABZEW
ACKZS
ACOPL
ADFOM
ADFZZ
AEIIZ
AFLEI
AI.
AJVHN
AWYRJ
BRMBE
CAG
CGR
COF
CUY
CVF
CYYVM
CZDIS
DRXRE
DWTOO
ECM
EIF
GROUPED_DOAJ
JENTW
LJTGL
M44
NPM
NUSFT
QQXMO
VH1
7X8
ID FETCH-LOGICAL-c366t-cc3fc155e6b89016e3e2ad5ad944ce84e7758152dd70d0dfd7dac259f55a8b33
ISSN 0891-6934
1607-842X
IngestDate Thu Jul 10 20:12:07 EDT 2025
Thu Apr 03 07:07:16 EDT 2025
Tue Jul 01 03:37:37 EDT 2025
Thu Apr 24 23:04:39 EDT 2025
Tue May 20 10:45:40 EDT 2025
IsPeerReviewed true
IsScholarly true
Issue 6
Keywords microRNA
systemic lupus erythematosus
Sjogren’s syndrome
Exosome
rheumatoid arthritis
Language English
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c366t-cc3fc155e6b89016e3e2ad5ad944ce84e7758152dd70d0dfd7dac259f55a8b33
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
PMID 27259064
PQID 1826698193
PQPubID 23479
PageCount 9
ParticipantIDs pubmed_primary_27259064
proquest_miscellaneous_1826698193
crossref_primary_10_1080_08916934_2016_1191477
crossref_citationtrail_10_1080_08916934_2016_1191477
informaworld_taylorfrancis_310_1080_08916934_2016_1191477
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2016-09-01
PublicationDateYYYYMMDD 2016-09-01
PublicationDate_xml – month: 09
  year: 2016
  text: 2016-09-01
  day: 01
PublicationDecade 2010
PublicationPlace England
PublicationPlace_xml – name: England
PublicationTitle Autoimmunity (Chur, Switzerland)
PublicationTitleAlternate Autoimmunity
PublicationYear 2016
Publisher Taylor & Francis
Publisher_xml – name: Taylor & Francis
References CIT0072
CIT0071
CIT0074
CIT0073
CIT0076
CIT0075
CIT0078
CIT0077
CIT0070
Clayton A. (CIT0027) 2004; 18
Zhang B. (CIT0009) 2014; 5
CIT0079
CIT0083
CIT0082
CIT0085
CIT0084
CIT0087
CIT0001
CIT0089
CIT0088
CIT0081
Hassani K. (CIT0034) 2013; 7
CIT0003
CIT0002
CIT0005
CIT0004
CIT0007
CIT0006
CIT0008
CIT0094
CIT0096
CIT0010
CIT0097
CIT0012
Ostman S. (CIT0080) 2005; 116
CIT0011
CIT0090
CIT0092
CIT0091
CIT0014
CIT0013
CIT0016
CIT0015
CIT0018
CIT0017
CIT0019
CIT0021
CIT0020
CIT0023
CIT0022
Perez-Hernandez J. (CIT0095) 2015; 10
Fabbri M. (CIT0058) 2012; 109
CIT0025
CIT0024
CIT0026
CIT0029
CIT0028
CIT0030
CIT0032
CIT0031
CIT0033
CIT0036
CIT0035
CIT0038
CIT0037
CIT0039
CIT0041
CIT0040
CIT0043
CIT0042
CIT0045
CIT0044
Palanisamy V. (CIT0086) 2010; 5
Barutta F. (CIT0093) 2013; 8
CIT0047
CIT0046
CIT0049
CIT0048
CIT0050
CIT0052
CIT0051
CIT0054
CIT0053
CIT0056
CIT0055
Thery C. (CIT0099) 2009; 9
CIT0057
CIT0059
Ichii O. (CIT0098) 2014; 9
CIT0061
CIT0060
CIT0063
CIT0062
CIT0065
CIT0064
CIT0067
CIT0100
CIT0066
CIT0069
CIT0102
CIT0068
CIT0101
References_xml – ident: CIT0102
  doi: 10.1016/j.jconrel.2011.11.021
– ident: CIT0081
  doi: 10.4049/jimmunol.181.2.1519
– ident: CIT0060
  doi: 10.1002/art.22276
– ident: CIT0032
  doi: 10.1111/j.1600-0854.2008.00734.x
– ident: CIT0021
  doi: 10.1083/jcb.147.3.599
– ident: CIT0079
  doi: 10.4049/jimmunol.0803477
– ident: CIT0017
  doi: 10.1182/blood-2005-01-0220
– ident: CIT0029
  doi: 10.1016/j.molimm.2007.11.021
– ident: CIT0041
  doi: 10.1016/j.cell.2008.12.027
– ident: CIT0067
  doi: 10.1007/s13277-013-0658-6
– ident: CIT0064
  doi: 10.1016/j.clim.2006.07.007
– ident: CIT0065
  doi: 10.1136/bmj.h5079
– ident: CIT0051
  doi: 10.1038/ncomms1285
– ident: CIT0077
  doi: 10.1007/978-1-59745-395-0_28
– ident: CIT0089
  doi: 10.1177/0961203309358187
– ident: CIT0013
  doi: 10.1016/j.semcancer.2014.05.003
– volume: 109
  start-page: E2110
  year: 2012
  ident: CIT0058
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.1209414109
– ident: CIT0016
  doi: 10.1111/j.1600-0854.2009.00963.x
– ident: CIT0090
  doi: 10.1073/pnas.0403453101
– ident: CIT0088
  doi: 10.3109/08916934.2014.921811
– ident: CIT0040
  doi: 10.1038/ncomms3980
– ident: CIT0031
  doi: 10.1126/stke.16pe8
– ident: CIT0028
  doi: 10.1111/j.1537-2995.2010.02909.x
– ident: CIT0057
  doi: 10.2174/22115366113029990012
– ident: CIT0071
  doi: 10.1007/s10238-013-0271-4
– ident: CIT0024
  doi: 10.1126/science.281.5373.96
– ident: CIT0035
  doi: 10.1016/j.pain.2014.04.029
– ident: CIT0097
  doi: 10.1093/ndt/gfv128
– ident: CIT0070
  doi: 10.1007/s12032-014-0148-8
– ident: CIT0008
  doi: 10.3389/fimmu.2014.00555
– ident: CIT0092
  doi: 10.1038/ki.2008.206
– ident: CIT0036
  doi: 10.1002/eji.201242909
– ident: CIT0078
  doi: 10.1111/j.1600-0897.2006.00435.x
– ident: CIT0054
  doi: 10.1016/j.jaci.2013.04.048
– ident: CIT0063
  doi: 10.1002/art.27501
– ident: CIT0074
  doi: 10.4049/jimmunol.174.10.6440
– volume: 18
  start-page: 977
  year: 2004
  ident: CIT0027
  publication-title: FASEB J.
  doi: 10.1096/fj.03-1094fje
– ident: CIT0020
  doi: 10.4049/jimmunol.172.4.2126
– volume: 5
  start-page: e8577
  year: 2010
  ident: CIT0086
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0008577
– ident: CIT0002
  doi: 10.1016/j.clinthera.2014.04.019
– ident: CIT0001
  doi: 10.3390/s120303359
– ident: CIT0046
  doi: 10.1016/j.nano.2014.03.014
– ident: CIT0056
  doi: 10.1073/pnas.0914843107
– ident: CIT0012
  doi: 10.1038/icb.2010.64
– ident: CIT0030
  doi: 10.3389/fimmu.2014.00144
– ident: CIT0047
  doi: 10.1182/blood-2011-08-374793
– ident: CIT0045
  doi: 10.1073/pnas.1311145110
– ident: CIT0069
  doi: 10.1016/j.canlet.2013.06.013
– ident: CIT0076
  doi: 10.1016/j.ymthe.2005.09.015
– ident: CIT0039
  doi: 10.1016/j.bbrc.2013.07.044
– ident: CIT0023
  doi: 10.1002/eji.200838374
– ident: CIT0052
  doi: 10.1038/ncb1929
– ident: CIT0004
  doi: 10.1034/j.1600-0854.2002.30502.x
– ident: CIT0087
  doi: 10.3109/08916934.2014.915955
– ident: CIT0006
  doi: 10.1186/1479-5876-9-86
– ident: CIT0003
  doi: 10.1016/j.clinbiochem.2013.10.020
– ident: CIT0026
  doi: 10.1111/sji.12247
– ident: CIT0062
  doi: 10.2337/db13-0859
– ident: CIT0096
  doi: 10.1177/0961203310389841
– ident: CIT0083
  doi: 10.1111/j.1365-2362.2010.02342.x
– ident: CIT0094
  doi: 10.1002/hep.25873
– volume: 10
  start-page: e0138618
  year: 2015
  ident: CIT0095
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0138618
– ident: CIT0018
  doi: 10.1016/j.bcmd.2005.05.002
– ident: CIT0073
  doi: 10.1038/cr.2011.196
– ident: CIT0042
  doi: 10.1111/imr.12059
– ident: CIT0048
  doi: 10.1186/1476-4598-10-117
– volume: 8
  start-page: e73798
  year: 2013
  ident: CIT0093
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0073798
– ident: CIT0038
  doi: 10.1016/j.immuni.2014.07.001
– ident: CIT0049
  doi: 10.3389/fimmu.2014.00043
– ident: CIT0084
  doi: 10.2217/bmm.13.63
– ident: CIT0050
  doi: 10.1111/imr.12013
– ident: CIT0059
  doi: 10.1038/nrrheum.2014.19
– ident: CIT0011
  doi: 10.1186/1757-2215-7-14
– ident: CIT0068
  doi: 10.4161/rna.7.5.13216
– ident: CIT0053
  doi: 10.1593/neo.122010
– ident: CIT0043
  doi: 10.1182/blood-2011-02-338004
– ident: CIT0101
  doi: 10.1038/nbt.1807
– volume: 5
  start-page: 518
  year: 2014
  ident: CIT0009
  publication-title: Front. Immunol
– ident: CIT0010
  doi: 10.1007/s00262-003-0472-x
– ident: CIT0025
  doi: 10.4049/jimmunol.177.7.4481
– ident: CIT0066
  doi: 10.14791/btrt.2014.2.1.1
– ident: CIT0037
  doi: 10.1016/j.immuni.2014.05.019
– volume: 9
  start-page: e110383
  year: 2014
  ident: CIT0098
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0110383
– volume: 116
  start-page: 464
  year: 2005
  ident: CIT0080
  publication-title: Immunology
  doi: 10.1111/j.1365-2567.2005.02245.x
– ident: CIT0015
  doi: 10.1038/ni854
– ident: CIT0055
  doi: 10.1016/j.chom.2012.08.010
– ident: CIT0033
  doi: 10.1074/jbc.M702277200
– ident: CIT0007
  doi: 10.1084/jem.183.3.1161
– ident: CIT0014
  doi: 10.1158/0008-5472.CAN-09-3276
– ident: CIT0072
  doi: 10.1155/2012/573528
– volume: 7
  start-page: e2185
  year: 2013
  ident: CIT0034
  publication-title: PLoS. Negl. Trop. Dis.
  doi: 10.1371/journal.pntd.0002185
– ident: CIT0022
  doi: 10.1007/s10059-013-0154-2
– ident: CIT0082
  doi: 10.4049/jimmunol.179.3.1969
– ident: CIT0091
  doi: 10.1038/ki.2010.106
– ident: CIT0044
  doi: 10.1111/boc.201400081
– ident: CIT0075
  doi: 10.4049/jimmunol.179.4.2242
– ident: CIT0005
  doi: 10.1016/j.gde.2014.03.006
– ident: CIT0061
  doi: 10.1002/art.21005
– volume: 9
  start-page: 581
  year: 2009
  ident: CIT0099
  publication-title: Nat. Rev. Immunol.
  doi: 10.1038/nri2567
– ident: CIT0019
  doi: 10.1016/j.bcp.2011.12.037
– ident: CIT0085
  doi: 10.1111/j.1601-0825.2009.01604.x
– ident: CIT0100
  doi: 10.3402/jev.v4.27066
SSID ssj0002764
Score 2.4731307
SecondaryResourceType review_article
Snippet Exosomes are small membrane-bound vesicles (30-100 nm) that are secreted by different types of cells and they have been well documented to resemble saucers or...
SourceID proquest
pubmed
crossref
informaworld
SourceType Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 357
SubjectTerms Animals
Autoimmune Diseases - drug therapy
Autoimmune Diseases - etiology
Autoimmune Diseases - metabolism
Autoimmunity
Biological Transport
Biomarkers
Exosome
Exosomes - metabolism
Humans
Immune System - cytology
Immune System - immunology
Immune System - metabolism
Immunomodulation
microRNA
MicroRNAs - genetics
MicroRNAs - metabolism
Molecular Targeted Therapy
rheumatoid arthritis
Sjogren's syndrome
systemic lupus erythematosus
Title Recent advances of exosomes in immune modulation and autoimmune diseases
URI https://www.tandfonline.com/doi/abs/10.1080/08916934.2016.1191477
https://www.ncbi.nlm.nih.gov/pubmed/27259064
https://www.proquest.com/docview/1826698193
Volume 49
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwELZgKxAXBOXR5SUjcUNZZWPHSY5boFohlVOQCpfIcRw1FSSomwjor2dsj7NZtag8LtHKlteR58v4G3sehLyKVb3UZR0GyoT_clGzIK0FfFemEpLmWihuApyPP4j1R_7-JD6Z3Jia6JK-XKiLK-NK_kWq0AZyNVGyfyHZ8U-hAX6DfOEJEobnH8kYOJ91EXf3-NYpQ__oNt1X62X1ujGxH9oUu8EaXS4z69B32IO3M5spQ135bkPPzRXv6eBKc31v-gsXGjw5PcgxdAGLcFv1PtjtTDZnflc0_j6Nbf00afp8KjvnuI9tePawFKNzlUNLfqkMyFR7ZctAZHhSqZ12FSFsidzWTx_Vr8tYijCb6lLmMlfjtsxcSYlLGh9dJGE2M5nx1RMLm7QOq8PsJtPGnptkLwKzIpqRvdXh28Ojce-OEpdwzL-8j_ky2divmmKHzezkuv29xWKZS36P3EWTg64cfu6TG7rdJ7dcEdKf--T2MbpXPCBrByjqAUW7mnpA0aalDjZ0CygKaKBbQFEPqIckP3qXv1kHWGojUEyIPlCK1QqopRZlCgxRaKYjWcWyyjhXOuU6AbsSqF5VJWEVVnWVVFKB5VzHsUxLxh6RWdu1-oBQHpbA0WUSxxGMrYRMVWay_mkuuQIyOyfcr1ihMA29qYbypVj6bLW40IVZ6AIXek4W47BvLg_LdQOyqTiK3mK1djAt2DVjX3rZFaBtzRWabHU3bApjjYsMWDSbk8dOqOPrRAksCDD8J_8x81NyZ_udPSOz_nzQz4H19uULhOovLnqjNQ
linkProvider EBSCOhost
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Recent+advances+of+exosomes+in+immune+modulation+and+autoimmune+diseases&rft.jtitle=Autoimmunity+%28Chur%2C+Switzerland%29&rft.au=Tan%2C+Lina&rft.au=Wu%2C+Haijing&rft.au=Liu%2C+Ying&rft.au=Zhao%2C+Ming&rft.date=2016-09-01&rft.pub=Taylor+%26+Francis&rft.issn=0891-6934&rft.eissn=1607-842X&rft.volume=49&rft.issue=6&rft.spage=357&rft.epage=365&rft_id=info:doi/10.1080%2F08916934.2016.1191477&rft.externalDocID=1191477
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0891-6934&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0891-6934&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0891-6934&client=summon