Adenosine Metabolism in COPD: A Study on Adenosine Levels, 5′-Nucleotidase, Adenosine Deaminase and Its Isoenzymes Activity in Serum, Lymphocytes and Erythrocytes

• Published in: Chronic obstructive pulmonary disease Vol. 15; no. 6; pp. 559 - 571
• Main Authors: Singh Patidar, Bhagwan, Meena, Anil, Kumar, Manoj, Menon, Balakrishnan, Rohil, Vishwajeet, Kumar Bansal, Surendra
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 02.11.2018
• Subjects: airways; inflammatory cells; Obstructive pulmonary diseases; purine metabolism; smoking; airways; purine metabolism; inflammatory cells; smoking; Obstructive pulmonary diseases

Adenosine is a signaling molecule which is produced in high concentrations during airway inflammation. Airway inflammation is a characteristic feature of COPD. Therefore, the current study was designed to evaluate the changes in adenosine metabolism in COPD and correlate these changes with severity...