Evaluating task-based brain network activity in pediatric subjects with an mTBI: mechanisms of functional compensation are symptom-level dependent

• Published in: Brain injury Vol. 33; no. 3; p. 383
• Main Authors: Holmes, Scott A, Singh-Saluja, Rajeet, Chen, Jen-Kai, Gagnon, Isabelle, Ptito, Alain
• Format: Journal Article
• Language: English
• Published: England 23.02.2019
• Subjects: Adolescent; Brain Concussion - diagnostic imaging; Brain Concussion - physiopathology; Brain Concussion - psychology; Brain Mapping; Decision Making; Female; Frontal Lobe - diagnostic imaging; Hippocampus - diagnostic imaging; Hippocampus - physiopathology; Humans; Magnetic Resonance Imaging; Male; Nerve Net - diagnostic imaging; Nerve Net - physiopathology; Neuropsychological Tests; Occipital Lobe - diagnostic imaging; Post-Concussion Syndrome - diagnosis; Post-Concussion Syndrome - diagnostic imaging; Post-Concussion Syndrome - psychology; Psychomotor Performance; Space Perception; functional MRI; adaptation; functional compensation; mild traumatic brain injury; spatial navigation

The diagnosis of a mild traumatic brain injury (mTBI) places large emphasis on patient-reported symptoms which has restricted our ability to evaluate patients. Task-based functional magnetic resonance imaging has the potential to act as an objective measurement of abnormal brain activity and inform...