Inducing ketogenesis via an enteral formulation in patients with acute brain injury:a phase II study

• Published in: Neurological research (New York) Vol. 42; no. 4; p. 275
• Main Authors: White, Hayden, Venkatesh, Balasubramanian, Jones, Mark, Kruger, Peter S, Walsham, James, Fuentes, Hesly
• Format: Journal Article
• Language: English
• Published: England 02.04.2020
• Subjects: Adult; Aged; Aged, 80 and over; Brain Injuries - blood; Brain Injuries - diagnosis; Brain Injuries - diet therapy; Diet, Ketogenic - methods; Enteral Nutrition - methods; Female; Humans; Male; Middle Aged; Prospective Studies; Respiration, Artificial - methods; traumatic brain injury; beta-hydroxybutyrate; Ketones; stroke; subarachnoid hemorrhage; acute brain injury

: Although extensively studied in children, the safety and tolerability of ketone supplementation in adults is unclear, particularly in the acute brain injury population. The purpose of this study was to examine the feasibility and safety of inducing ketosis using an enteric ketogenic formulation an...