Novel antifungal agents: a patent review (2013 - present)

• Published in: Expert opinion on therapeutic patents Vol. 27; no. 4; p. 415
• Main Authors: Victoria Castelli, María, Gabriel Derita, Marcos, Noelí López, Silvia
• Format: Journal Article
• Language: English
• Published: England 03.04.2017
• Subjects: Animals; Antifungal Agents - adverse effects; Antifungal Agents - pharmacokinetics; Antifungal Agents - pharmacology; Drug Design; Drug Discovery - methods; Humans; Immunocompromised Host; Mycoses - drug therapy; Mycoses - epidemiology; Patents as Topic; antifungal compounds; antifungal peptides; fungal cell wall; Polyenes; azole-based antifungal drugs

Superficial infections involving the skin and mucosa are the most common fungal disease in humans. Fungi can also produce invasive infections (IFI), which are increasing in incidence among the growing population of immunocompromised patients, and are characterized by a high mortality rate. Amphoteri...