The pivotal role of inflammatory factors in glaucoma: a systematic review

• Published in: Frontiers in immunology Vol. 16; p. 1577200
• Main Authors: Lin, Bin, Li, Dongkan
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 2025
• Subjects: Animals; Biomarkers - metabolism; glaucoma; Glaucoma - etiology; Glaucoma - immunology; Glaucoma - metabolism; Glaucoma - therapy; Humans; Inflammation - immunology; Inflammation - metabolism; Inflammation Mediators - metabolism; inflammatory factors; neuroinflammation; pathogenesis; therapeutic targets; pathogenesis; therapeutic targets; neuroinflammation; inflammatory factors; glaucoma

Glaucoma, a leading cause of irreversible vision loss, is becoming more prevalent with the aging population, burdening patients, families, and society. In the past, the role of inflammatory factors in its pathogenesis was overlooked. This systematic review, based on a PubMed search and strict screen...