Topical therapy for methicillin-resistant Staphylococcus aureus colonization: impact on infection risk

• Published in: Infection control and hospital epidemiology Vol. 30; no. 7; p. 623
• Main Authors: Robicsek, Ari, Beaumont, Jennifer L, Thomson, Jr, Richard B, Govindarajan, Geetha, Peterson, Lance R
• Format: Journal Article
• Language: English
• Published: United States 01.07.2009
• Subjects: Administration, Topical; Adolescent; Adult; Aged; Anti-Bacterial Agents - administration & dosage; Anti-Bacterial Agents - therapeutic use; Anti-Infective Agents, Local - administration & dosage; Anti-Infective Agents, Local - therapeutic use; Carrier State - drug therapy; Carrier State - epidemiology; Carrier State - prevention & control; Child; Child, Preschool; Chlorhexidine - administration & dosage; Chlorhexidine - analogs & derivatives; Chlorhexidine - therapeutic use; Cohort Studies; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Male; Methicillin-Resistant Staphylococcus aureus - drug effects; Methicillin-Resistant Staphylococcus aureus - isolation & purification; Middle Aged; Mupirocin - administration & dosage; Mupirocin - therapeutic use; Risk Factors; Staphylococcal Infections - drug therapy; Staphylococcal Infections - epidemiology; Staphylococcal Infections - prevention & control; Treatment Outcome; Young Adult

We evaluated the usefulness of topical decolonization therapy for reducing the risk of methicillin-resistant Staphylococcus aureus (MRSA) infection among MRSA-colonized inpatients. Retrospective cohort study. Three hospitals with universal surveillance for MRSA; at their physician's discretion,...