An association between average daily sleep duration and gallstones in US adults

Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence of gallstones in adults has not been thoroughly investigated. This study analyzes data from 7,441 individuals from the NHANES 2017–2020 dataset, usin...

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Published inScientific reports Vol. 15; no. 1; pp. 4573 - 10
Main Authors Fang, Yong, Xu, Qiuyuan, Xu, Jia, Wang, HaiHua
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 07.02.2025
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Abstract Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence of gallstones in adults has not been thoroughly investigated. This study analyzes data from 7,441 individuals from the NHANES 2017–2020 dataset, using exclusion criteria to refine the participant pool. Employing multivariate logistic regression and subgroup analyses while controlling for potential confounders, we assessed the association between average daily sleep duration and the prevalence of gallstones. Our results revealed a statistically significant inverse association (OR = 0.92; 95% CI: 0.86, 0.99; p  = 0.0236). This association was consistent across various demographic and health-related subgroups. Interestingly, the inflection points were observed among middle-aged adults (40–60 years) and individuals with diabetes. These findings could inform public health strategies on sleep management, potentially aiding in the prevention of gallstones within these populations.
AbstractList Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence of gallstones in adults has not been thoroughly investigated. This study analyzes data from 7,441 individuals from the NHANES 2017-2020 dataset, using exclusion criteria to refine the participant pool. Employing multivariate logistic regression and subgroup analyses while controlling for potential confounders, we assessed the association between average daily sleep duration and the prevalence of gallstones. Our results revealed a statistically significant inverse association (OR = 0.92; 95% CI: 0.86, 0.99; p = 0.0236). This association was consistent across various demographic and health-related subgroups. Interestingly, the inflection points were observed among middle-aged adults (40-60 years) and individuals with diabetes. These findings could inform public health strategies on sleep management, potentially aiding in the prevention of gallstones within these populations.
Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence of gallstones in adults has not been thoroughly investigated. This study analyzes data from 7,441 individuals from the NHANES 2017-2020 dataset, using exclusion criteria to refine the participant pool. Employing multivariate logistic regression and subgroup analyses while controlling for potential confounders, we assessed the association between average daily sleep duration and the prevalence of gallstones. Our results revealed a statistically significant inverse association (OR = 0.92; 95% CI: 0.86, 0.99; p = 0.0236). This association was consistent across various demographic and health-related subgroups. Interestingly, the inflection points were observed among middle-aged adults (40-60 years) and individuals with diabetes. These findings could inform public health strategies on sleep management, potentially aiding in the prevention of gallstones within these populations.Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence of gallstones in adults has not been thoroughly investigated. This study analyzes data from 7,441 individuals from the NHANES 2017-2020 dataset, using exclusion criteria to refine the participant pool. Employing multivariate logistic regression and subgroup analyses while controlling for potential confounders, we assessed the association between average daily sleep duration and the prevalence of gallstones. Our results revealed a statistically significant inverse association (OR = 0.92; 95% CI: 0.86, 0.99; p = 0.0236). This association was consistent across various demographic and health-related subgroups. Interestingly, the inflection points were observed among middle-aged adults (40-60 years) and individuals with diabetes. These findings could inform public health strategies on sleep management, potentially aiding in the prevention of gallstones within these populations.
Abstract Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence of gallstones in adults has not been thoroughly investigated. This study analyzes data from 7,441 individuals from the NHANES 2017–2020 dataset, using exclusion criteria to refine the participant pool. Employing multivariate logistic regression and subgroup analyses while controlling for potential confounders, we assessed the association between average daily sleep duration and the prevalence of gallstones. Our results revealed a statistically significant inverse association (OR = 0.92; 95% CI: 0.86, 0.99; p = 0.0236). This association was consistent across various demographic and health-related subgroups. Interestingly, the inflection points were observed among middle-aged adults (40–60 years) and individuals with diabetes. These findings could inform public health strategies on sleep management, potentially aiding in the prevention of gallstones within these populations.
Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence of gallstones in adults has not been thoroughly investigated. This study analyzes data from 7,441 individuals from the NHANES 2017–2020 dataset, using exclusion criteria to refine the participant pool. Employing multivariate logistic regression and subgroup analyses while controlling for potential confounders, we assessed the association between average daily sleep duration and the prevalence of gallstones. Our results revealed a statistically significant inverse association (OR = 0.92; 95% CI: 0.86, 0.99; p  = 0.0236). This association was consistent across various demographic and health-related subgroups. Interestingly, the inflection points were observed among middle-aged adults (40–60 years) and individuals with diabetes. These findings could inform public health strategies on sleep management, potentially aiding in the prevention of gallstones within these populations.
ArticleNumber 4573
Author Xu, Qiuyuan
Xu, Jia
Wang, HaiHua
Fang, Yong
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Snippet Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence of...
Abstract Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence...
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SubjectTerms 692/308
692/699
Adult
Aged
Alcohol
Asymptomatic
Average daily sleep duration
Blood pressure
Body mass index
Calculi
Cholesterol
Cross-sectional study
Diabetes
Diabetes mellitus
Exercise
Female
Gallstones
Gallstones - epidemiology
Gender
Humanities and Social Sciences
Humans
Hypertension
Investigations
Male
Medical diagnosis
Middle Aged
multidisciplinary
NHANES
Nutrition Surveys
Prevalence
Public health
Questionnaires
Regression analysis
Risk Factors
Science
Science (multidisciplinary)
Sleep
Sleep - physiology
Sleep Duration
Smoking
Standard deviation
Statistical analysis
Thyroid gland
Time Factors
Triglycerides
United States - epidemiology
Variables
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Title An association between average daily sleep duration and gallstones in US adults
URI https://link.springer.com/article/10.1038/s41598-025-89157-z
https://www.ncbi.nlm.nih.gov/pubmed/39915625
https://www.proquest.com/docview/3164194776
https://www.proquest.com/docview/3164397701
https://doaj.org/article/96f78922fbaa4f89b0437c9c61298e2d
Volume 15
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