PDGFR-β/Cav1-induced autophagy via mTOR/FIP200/ATG13 activation in cancer-associated fibroblasts promotes the malignant progression of breast cancer - Zhang, Lifang; Wang, Keqin; Zhang, Jianbo; Qian, Xianzhe; Zhang, Xiaoan; Wang, Yi; Hu, Quan; Zhan, Ziyi; Hu, Wending; Lin, Hui; Liu, Xiaoming; Xiong, Lixia (Journal of translational medicine, 2025)
Keywords: Animals; Autophagy; Autophagy-Related Proteins - metabolism; Breast cancer; Breast Neoplasms - metabolism; Breast Neoplasms - pathology; Cancer-associated fibroblasts; Cancer-Associated Fibroblasts - metabolism; Cancer-Associated Fibroblasts - pathology; Caveolin 1 - metabolism; Caveolin-1; Cell Line, Tumor; Cell Movement; Disease Progression; Female; Humans; Mice; Neoplasm Invasiveness; PDGFR-β; Receptor, Platelet-Derived Growth Factor beta - metabolism; Signal Transduction; TOR Serine-Threonine Kinases - metabolism; Tumor Microenvironment; Caveolin-1; Cancer-associated fibroblasts; PDGFR-β; Breast cancer; Autophagy