Research progress of colorectal cancer in genomic and transcriptomic at multi-level

• Published in: Frontiers in genetics Vol. 16; p. 1533817
• Main Authors: Wen, Qinglian, Han, Shuangyan, Cui, Yongxia
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 2025
• Subjects: CRC (colorectal cancer); evolutionary genomics; single-cell genomics; tumor heterogeneity; tumor microenvironment; single-cell genomics; evolutionary genomics; tumor microenvironment; CRC (colorectal cancer); tumor heterogeneity

Colorectal cancer is a common malignant tumor in the gastrointestinal tract, and the mechanisms of its occurrence, development, and metastasis have always been the focus of the medical community’s attention. The study of CRC genetic mechanisms began with the identification of oncogenes or tumor supp...