The N-6 methyladenosine dynamics in STEMI and the effect of IL-6 inhibition - a hypothesis generating sub-study of the ASSAIL-MI trial - Dahl, Tuva B.; Quiles-Jiménez, Ana; Broch, Kaspar; Anstensrud, Anne Kristine; Gullestad, Lars; Andersen, Geir Ø.; Kleveland, Ola; Øgaard, Jonas; Bjerkeli, Vigdis; Rashidi, Azita; Yang, Kuan; Holven, Kirsten B.; et al. (Frontiers in immunology, 2025)
Keywords: Adenosine - analogs & derivatives; Adenosine - blood; Adenosine - metabolism; Aged; epitranscriptome; Female; Humans; inflammation; Interleukin-6 - antagonists & inhibitors; Male; Middle Aged; N6-methyladenosine (m6A); RNA methylation; RNA, Messenger - genetics; ST Elevation Myocardial Infarction - blood; ST Elevation Myocardial Infarction - drug therapy; ST Elevation Myocardial Infarction - genetics; ST Elevation Myocardial Infarction - metabolism; STEMI; tocilizumab; STEMI; N6-methyladenosine (m6A); tocilizumab; epitranscriptome; inflammation; RNA methylation