Plasma Metabolites in Early Sepsis Identify Distinct Clusters Defined by Plasma Lipids

• Published in: Critical care explorations Vol. 3; no. 8; p. e0478
• Main Authors: Rogers, Angela J., Leligdowicz, Aleksandra, Contrepois, Kévin, Jauregui, Alejandra, Vessel, Kathryn, Deiss, Thomas J., Belzer, Annika, Liu, Tom, Lippi, Matthew, Ke, Serena, Ross, Erin, Zhou, Hanjing, Hendrickson, Carolyn, Gomez, Antonio, Sinha, Pratik, Kangelaris, Kirsten N., Liu, Kathleen D., Calfee, Carolyn S., Matthay, Michael A.
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 29.07.2021; Wolters Kluwer
• Subjects: Original Clinical Report

OBJECTIVES: Unbiased global metabolomic profiling has not been used to identify distinct subclasses in patients with early sepsis and sepsis-associated acute respiratory distress syndrome. In this study, we examined whether the plasma metabolome reflects systemic illness in early sepsis and in acute...