Polyglycolide-based blends for drug delivery: A differential scanning calorimetry study of the melting behavior

• Published in: Journal of applied polymer science Vol. 89; no. 11; pp. 2937 - 2939
• Main Authors: Dickers, Kirsten J., Huatan, Hiep, Cameron, Ruth E.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 12.09.2003; Wiley
• Subjects: Applied sciences; blending; blends; differential scanning calorimetry (DSC); Exact sciences and technology; miscibility; Organic polymers; Physicochemistry of polymers; Properties and characterization; Thermal and thermodynamic properties; differential scanning calorimetry (DSC); Melting; Polymer blends; Valerate(hydroxy) copolymer; Lactic acid copolymer; Butyrate(hydroxy) copolymer; Experimental study; Glycolic acid polymer; Caprolactone copolymer; miscibility; Aliphatic polymer; blending; Polycaprolactone; blends
• ISSN: 0021-8995; 1097-4628
• DOI: 10.1002/app.12353

The melting behavior of polyglycolide (PGA) with eight other biodegradable polymers was investigated to determine whether forming a blend could be used as a method of lowering the melting point of PGA. Blends were prepared by melt processing in differential scanning calorimetry (DSC) pans and were then analyzed by DSC. In every case, a comparison of the blend DSC plot with those of the two individual components showed that the melting behavior of PGA remained unchanged by blending. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 89: 2937–2939, 2003