Increased Rho kinase activity in patients with heart ischemia/reperfusion

• Published in: Perfusion Vol. 34; no. 1; p. 15
• Main Authors: Zhang, Juan, Xu, Fei, Liu, Xiao-Bo, Bi, Shao-Jie, Lu, Qing-Hua
• Format: Journal Article
• Language: English
• Published: England 01.01.2019
• Subjects: Biomarkers - metabolism; C-Reactive Protein - metabolism; Case-Control Studies; Female; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; rho-Associated Kinases - metabolism; ST Elevation Myocardial Infarction - enzymology; ST Elevation Myocardial Infarction - therapy; Troponin I - metabolism; percutaneous coronary intervention; Rho kinase; myocardial reperfusion injury; acute myocardial infarction; patients

Rho kinase is a downstream effector of Rho GTPase that is known to regulate various pathological processes. The aim of this study was to evaluate the regulation of Rho kinase activity in leukocytes in patients with ischemia/reperfusion (I/R) injury. We investigated 38 patients with acute ST-segment...