Systemic lupus erythematosus–associated diffuse alveolar hemorrhage: a single-center, matched case–control study in China

• Published in: Lupus Vol. 29; no. 7; pp. 795 - 803
• Main Authors: Sun, Yiduo, Zhou, Cong, Zhao, Jiuliang, Wang, Qian, Xu, Dong, Zhang, Shangzhu, Shen, Min, Hou, Yong, Tian, Xinping, Li, Mengtao, Zeng, Xiaofeng
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.06.2020; Sage Publications Ltd
• Subjects: Administration, Intravenous; Adult; Alveoli; Autoantibodies - immunology; C-reactive protein; C-Reactive Protein - metabolism; Case-Control Studies; China; Cyclophosphamide; Cyclophosphamide - administration & dosage; Diagnosis; Female; Health risk assessment; Hemorrhage; Hemorrhage - complications; Hemorrhage - drug therapy; Hemorrhage - pathology; Humans; Intravenous administration; Logistic Models; Lung Diseases - complications; Lung Diseases - drug therapy; Lung Diseases - pathology; Lupus; Lupus Erythematosus, Systemic - complications; Lupus nephritis; Lupus Nephritis - complications; Male; Mechanical ventilation; Medical prognosis; Mortality; Multivariate Analysis; Nephritis; Patients; Pulmonary Alveoli - pathology; Risk Factors; Survival Analysis; Systemic lupus erythematosus; Thrombocytopenia; Thrombocytopenia - complications; Treatment Outcome; Young Adult; China; diffuse alveolar hemorrhage; pulmonary hemorrhage; Systemic lupus erythematosus

Background This study described clinical characteristics and outcome in systemic lupus erythematosus (SLE) patients with diffuse alveolar hemorrhage (DAH), and investigated risk factors and prognostic factors for DAH. Methods We conducted a retrospective nested case–control analysis in a single-cent...