Multidrug- and Extensively Drug-Resistant Acinetobacter baumannii in a Tertiary Hospital from Brazil: The Importance of Carbapenemase Encoding Genes and Epidemic Clonal Complexes in a 10-Year Study

• Published in: Microbial drug resistance (Larchmont, N.Y.) Vol. 25; no. 9; p. 1365
• Main Authors: Romanin, Priscila, Palermo, Raquel Lima, Cavalini, Jônatas Fernando, Fávaro, Larissa Dos Santos, De Paula-Petroli, Suelen Balero, Fernandes, Eduardo Vignoto, Dos Anjos Szczerepa, Márcia Maria, Tognim, Maria Cristina Bronharo, Yamada-Ogatta, Sueli Fumie, Carrara-Marroni, Floristher Elaine, Yamauchi, Lucy Megumi
• Format: Journal Article
• Language: English
• Published: United States 01.11.2019
• Subjects: Acinetobacter baumannii - drug effects; Acinetobacter baumannii - genetics; Acinetobacter baumannii - isolation & purification; Acinetobacter Infections - drug therapy; Acinetobacter Infections - epidemiology; Acinetobacter Infections - microbiology; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents - pharmacology; Bacterial Proteins - genetics; beta-Lactamases - genetics; Brazil; Carbapenems - pharmacology; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Female; Humans; Infant; Infant, Newborn; Male; Microbial Sensitivity Tests; Middle Aged; Tertiary Care Centers; Young Adult; Brazil; genetic diversity; Tn2006; OXA-23; carbapenem; OXA-253; epidemic clonal complex

This study aimed to characterize the main mechanisms of acquired antimicrobial resistance of 103 multidrug-resistant isolated from bloodstream from 2006 to 2016 from a hospital in Londrina, Brazil. All 103 isolates were identified as by amplification of the and B genes. Mortality was observed in the...