Carbon dots: Applications in bioimaging and theranostics

[Display omitted] Carbon dots are a carbonaceous nanomaterial that were discovered accidentally and are now drawing significant attention as a new quantum-sized fluorescent nanoparticle. Carbon dots are biocompatible, non-toxic, photostable, and easily functionalized with good photoluminescence and...

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Published inInternational journal of pharmaceutics Vol. 564; pp. 308 - 317
Main Authors Boakye-Yiadom, Kofi Oti, Kesse, Samuel, Opoku-Damoah, Yaw, Filli, Mensura Sied, Aquib, Md, Joelle, Mily Maviah Bazezy, Farooq, Muhammad Asim, Mavlyanova, Rukhshona, Raza, Faisal, Bavi, Rohit, Wang, Bo
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 10.06.2019
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Abstract [Display omitted] Carbon dots are a carbonaceous nanomaterial that were discovered accidentally and are now drawing significant attention as a new quantum-sized fluorescent nanoparticle. Carbon dots are biocompatible, non-toxic, photostable, and easily functionalized with good photoluminescence and water solubility. Due to these unique properties, they are used broadly in live cell imaging, catalysis, electronics, biosensing, power, targeted drug delivery, and other biomedical applications. Here, we review the recent development of carbon dots in nanomedicine from their use in drug carriers to imaging agents to multifunctional theranostic systems. Finally, we discuss the challenges and views on next-generation carbon dot-based theranostics for clinical applications.
AbstractList [Display omitted] Carbon dots are a carbonaceous nanomaterial that were discovered accidentally and are now drawing significant attention as a new quantum-sized fluorescent nanoparticle. Carbon dots are biocompatible, non-toxic, photostable, and easily functionalized with good photoluminescence and water solubility. Due to these unique properties, they are used broadly in live cell imaging, catalysis, electronics, biosensing, power, targeted drug delivery, and other biomedical applications. Here, we review the recent development of carbon dots in nanomedicine from their use in drug carriers to imaging agents to multifunctional theranostic systems. Finally, we discuss the challenges and views on next-generation carbon dot-based theranostics for clinical applications.
Carbon dots are a carbonaceous nanomaterial that were discovered accidentally and are now drawing significant attention as a new quantum-sized fluorescent nanoparticle. Carbon dots are biocompatible, non-toxic, photostable, and easily functionalized with good photoluminescence and water solubility. Due to these unique properties, they are used broadly in live cell imaging, catalysis, electronics, biosensing, power, targeted drug delivery, and other biomedical applications. Here, we review the recent development of carbon dots in nanomedicine from their use in drug carriers to imaging agents to multifunctional theranostic systems. Finally, we discuss the challenges and views on next-generation carbon dot-based theranostics for clinical applications.Carbon dots are a carbonaceous nanomaterial that were discovered accidentally and are now drawing significant attention as a new quantum-sized fluorescent nanoparticle. Carbon dots are biocompatible, non-toxic, photostable, and easily functionalized with good photoluminescence and water solubility. Due to these unique properties, they are used broadly in live cell imaging, catalysis, electronics, biosensing, power, targeted drug delivery, and other biomedical applications. Here, we review the recent development of carbon dots in nanomedicine from their use in drug carriers to imaging agents to multifunctional theranostic systems. Finally, we discuss the challenges and views on next-generation carbon dot-based theranostics for clinical applications.
Carbon dots are a carbonaceous nanomaterial that were discovered accidentally and are now drawing significant attention as a new quantum-sized fluorescent nanoparticle. Carbon dots are biocompatible, non-toxic, photostable, and easily functionalized with good photoluminescence and water solubility. Due to these unique properties, they are used broadly in live cell imaging, catalysis, electronics, biosensing, power, targeted drug delivery, and other biomedical applications. Here, we review the recent development of carbon dots in nanomedicine from their use in drug carriers to imaging agents to multifunctional theranostic systems. Finally, we discuss the challenges and views on next-generation carbon dot-based theranostics for clinical applications.
Author Mavlyanova, Rukhshona
Wang, Bo
Bavi, Rohit
Kesse, Samuel
Opoku-Damoah, Yaw
Joelle, Mily Maviah Bazezy
Farooq, Muhammad Asim
Boakye-Yiadom, Kofi Oti
Raza, Faisal
Filli, Mensura Sied
Aquib, Md
Author_xml – sequence: 1
  givenname: Kofi Oti
  surname: Boakye-Yiadom
  fullname: Boakye-Yiadom, Kofi Oti
  organization: Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China
– sequence: 2
  givenname: Samuel
  orcidid: 0000-0002-0570-1311
  surname: Kesse
  fullname: Kesse, Samuel
  organization: Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China
– sequence: 3
  givenname: Yaw
  surname: Opoku-Damoah
  fullname: Opoku-Damoah, Yaw
  organization: Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China
– sequence: 4
  givenname: Mensura Sied
  surname: Filli
  fullname: Filli, Mensura Sied
  organization: Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China
– sequence: 5
  givenname: Md
  surname: Aquib
  fullname: Aquib, Md
  organization: Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China
– sequence: 6
  givenname: Mily Maviah Bazezy
  surname: Joelle
  fullname: Joelle, Mily Maviah Bazezy
  organization: Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China
– sequence: 7
  givenname: Muhammad Asim
  surname: Farooq
  fullname: Farooq, Muhammad Asim
  organization: Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China
– sequence: 8
  givenname: Rukhshona
  surname: Mavlyanova
  fullname: Mavlyanova, Rukhshona
  organization: Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China
– sequence: 9
  givenname: Faisal
  surname: Raza
  fullname: Raza, Faisal
  organization: Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China
– sequence: 10
  givenname: Rohit
  surname: Bavi
  fullname: Bavi, Rohit
  organization: State Key Laboratory of Natural Medicines, Department of Biomedical Engineering, School of Engineering, China Pharmaceutical University, Nanjing 210009, China
– sequence: 11
  givenname: Bo
  surname: Wang
  fullname: Wang, Bo
  email: bwangcpu@163.com, bowang@cpu.edu.cn
  organization: Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China
BackLink https://www.ncbi.nlm.nih.gov/pubmed/31015004$$D View this record in MEDLINE/PubMed
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Keywords Carbon dots
Diagnostics
Nanomedicine
Theranostics
Therapeutics
Language English
License Copyright © 2019. Published by Elsevier B.V.
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Snippet [Display omitted] Carbon dots are a carbonaceous nanomaterial that were discovered accidentally and are now drawing significant attention as a new...
Carbon dots are a carbonaceous nanomaterial that were discovered accidentally and are now drawing significant attention as a new quantum-sized fluorescent...
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SubjectTerms Carbon dots
Diagnostics
Nanomedicine
Theranostics
Therapeutics
Title Carbon dots: Applications in bioimaging and theranostics
URI https://dx.doi.org/10.1016/j.ijpharm.2019.04.055
https://www.ncbi.nlm.nih.gov/pubmed/31015004
https://www.proquest.com/docview/2213927065
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