Polymorphisms in CYP1A2, CYP2C9 and ABCB1 affect agomelatine pharmacokinetics - Saiz-Rodríguez, Miriam; Ochoa, Dolores; Belmonte, Carmen; Román, Manuel; Vieira de Lara, Danilo; Zubiaur, Pablo; Koller, Dora; Mejía, Gina; Abad-Santos, Francisco (Journal of psychopharmacology (Oxford), 2019)
Keywords: Acetamides - blood; Acetamides - pharmacokinetics; Acetamides - pharmacology; Adolescent; Adult; Alleles; Antidepressive Agents - blood; Antidepressive Agents - pharmacokinetics; Antidepressive Agents - pharmacology; ATP Binding Cassette Transporter, Subfamily B - genetics; Blood Pressure - drug effects; Cytochrome P-450 CYP1A2 - genetics; Cytochrome P-450 CYP2C9 - genetics; Electrocardiography - drug effects; Female; Genotype; Healthy Volunteers; Heart Rate - drug effects; Humans; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide - genetics; Young Adult; pharmacokinetics; Pharmacogenetics; cytochrome P450; agomelatine; antidepressant