Extending multivariate- t linear mixed models for multiple longitudinal data with censored responses and heavy tails

• Published in: Statistical methods in medical research Vol. 27; no. 1; p. 48
• Main Authors: Wang, Wan-Lun, Lin, Tsung-I, Lachos, Victor H
• Format: Journal Article
• Language: English
• Published: England 01.01.2018
• Subjects: multivariate longitudinal data; censored data; outliers; AIDS clinical trials; ECME algorithm

The analysis of complex longitudinal data is challenging due to several inherent features: (i) more than one series of responses are repeatedly collected on each subject at irregularly occasions over a period of time; (ii) censorship due to limits of quantification of responses arises left- and/or r...