Identifying iatrogenic depression using confirmatory factor analysis of the Center for Epidemiologic Studies Depression Scale in patients prescribed a verapamil-sustained-release-led or atenolol-led hypertension treatment strategy

• Published in: Research in social and administrative pharmacy Vol. 8; no. 4; pp. 309 - 320
• Main Authors: Wilson, Debbie L., Ried, L. Douglas
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2012
• Subjects: Adrenergic beta-1 Receptor Antagonists - adverse effects; Affect - drug effects; Aged; Aged, 80 and over; Antihypertensive Agents - adverse effects; Atenolol - adverse effects; Blood Pressure - drug effects; Calcium Channel Blockers - adverse effects; Chi-Square Distribution; Coronary artery disease; Delayed-Action Preparations; Depression; Depression - chemically induced; Depression - diagnosis; Depression - psychology; Depressive symptoms; Factor analysis; Factor Analysis, Statistical; Female; Happiness; Humans; Hypertension; Hypertension - drug therapy; Hypertension - physiopathology; Iatrogenic; Iatrogenic Disease; Interpersonal Relations; Male; Measurement equivalence; Middle Aged; Predictive Value of Tests; Prospective Studies; Psychiatric Status Rating Scales; Risk Assessment; Risk Factors; Self Report; Statistical; Time Factors; Treatment Outcome; United States; Verapamil - adverse effects; United States; Hypertension; Treatment outcome; Factor analysis; Measurement equivalence; Iatrogenic; Statistical; Depression; Depressive symptoms; Coronary artery disease

β-blockers and calcium channel blockers are highly effective medications indicated for treatment and prevention of hypertension. However, the literature regarding the potential depressive effects of β-blockers and calcium channel blockers is equivocal regarding whether one or both are associated wit...