Molecular strategies in Metazoan genomic evolution

• Published in: Gene Vol. 300; no. 1-2; pp. 195 - 201
• Main Authors: Saccone, Cecilia, Barome, Pierre Olivier, D'Erchia, Anna Maria, D'Errico, Ilenia, Pesole, Graziano, Sbisà, Elisabetta, Tullo, Apollonia
• Format: Journal Article
• Language: English
• Published: Netherlands 30.10.2002
• Subjects: Alternative Splicing; Animals; Binding Sites - genetics; Cell Nucleus - genetics; DNA, Mitochondrial - genetics; DNA-Binding Proteins - genetics; Evolution, Molecular; Genes - genetics; Genes, Tumor Suppressor; Genome; Humans; Membrane Proteins; Nuclear Proteins - genetics; Phosphoproteins - genetics; Trans-Activators - genetics; Transcription Factors; Tumor Protein p73; Tumor Suppressor Protein p53 - genetics; Tumor Suppressor Proteins

During the evolution of Metazoa, the mitochondrial genome has remained practically unchanged as indicated by its small size and constant gene content in each lineage, although several evolutionary processes have taken place. In contrast, the nuclear genome of Metazoa has undergone dramatic changes,...