Three-dimensional imaging and computational quantitation as a novel approach to assess nerve fibers, enteric glial cells, mast cells, and the proximity of mast cells to the nerve fibers in human sigmoid mucosal biopsies from healthy subjects - Yuan, Pu-Qing; Li, Tao; Mahurkar-Joshi, Swapna; Sohn, Jessica; Chang, Lin; Taché, Yvette (Journal of neuroscience methods, 2025)
Keywords: 3D imaging; Adult; Biopsy; Colon, Sigmoid - cytology; Colon, Sigmoid - innervation; Computerized quantitation; Enteric Nervous System - cytology; Female; Humans; Imaging, Three-Dimensional - methods; Intestinal Mucosa - cytology; Intestinal Mucosa - innervation; Male; Mast cells; Mast Cells - cytology; Nerve Fibers; Neuroglia - cytology; Sigmoid mucosa biopsy; Tissue clearing; Tissue clearing; Nerve fibers; Mast cells; 3D imaging; Sigmoid mucosa biopsy; Computerized quantitation