Sign tracking predicts cue-induced but not drug-primed reinstatement to methamphetamine seeking in rats: Effects of oxytocin treatment

• Published in: Journal of psychopharmacology (Oxford) Vol. 34; no. 11; p. 1271
• Main Authors: Everett, Nicholas A, Carey, Harry A, Cornish, Jennifer L, Baracz, Sarah J
• Format: Journal Article
• Language: English
• Published: United States 01.11.2020
• Subjects: sign tracking; oxytocin; relapse; incentive salience; Methamphetamine

The incentive sensitisation theory of addiction posits that drug-associated stimuli become imbued with incentive motivational properties, driving pathological drug seeking. However, pre-existing variability in the incentive salience to non-drug reward cues ('sign trackers' (STs); 'goa...