In Vitro Activity of a Novel Quinolone, UB-8902, Against Ofloxacin-Resistant Mycobacterium tuberculosis Isolates

• Published in: Microbial drug resistance (Larchmont, N.Y.)
• Main Authors: Tudó, Griselda, Lopez-Gavin, Alexandre, Portell-Buj, Elena, Freixes, Joan, Vila, Jordi, Roman, Angely, Monté, Maria Rosa, Gonzalez-Martin, Julian
• Format: Journal Article
• Language: English
• Published: United States 01.09.2020
• Subjects: in vitro susceptibility; fluoroquinolones; Mycobacterium tuberculosis; UB-8902

The main objective of this study was to compare activities of a novel fluoroquinolone (FQ), UB-8902, with ofloxacin (OFX), levofloxacin (LFX), and moxifloxacin (MOX) against isolates. Eleven OFX-resistant and 11 drug-susceptible clinical isolates were studied. Individual minimum inhibitory concentra...