High Rate of Failure After Matrix-Assisted Autologous Chondrocyte Transplantation in Osteoarthritic Knees at 15 Years of Follow-up

• Published in: The American journal of sports medicine Vol. 47; no. 9; p. 2116
• Main Authors: Andriolo, Luca, Reale, Davide, Di Martino, Alessandro, Zaffagnini, Stefano, Vannini, Francesca, Ferruzzi, Alberto, Filardo, Giuseppe
• Format: Journal Article
• Language: English
• Published: United States 01.07.2019
• Subjects: Adult; Arthroplasty, Replacement, Knee - statistics & numerical data; Cartilage, Articular - surgery; Chondrocytes - transplantation; Female; Follow-Up Studies; Humans; Knee Joint - surgery; Male; Middle Aged; Orthopedic Procedures - methods; Reoperation - statistics & numerical data; Transplantation, Autologous; Visual Analog Scale; knee; matrix-assisted autologous chondrocyte implantation; failure; osteoarthritis; cartilage

Chondral and osteochondral lesions in osteoarthritic knees of young patients remain challenging for orthopaedic surgeons, due to a combination of high functional demands and limited indications for joint replacement in this population. The possibility of extending the indication of cartilage regener...