Genotoxicity biomarkers associated with exposure to traffic and near-road atmospheres: a review

• Published in: Mutagenesis Vol. 28; no. 5; pp. 485 - 505
• Main Author: DeMarini, D. M.
• Format: Journal Article
• Language: English
• Published: England 01.09.2013
• Subjects: Air Pollutants - toxicity; Biomarkers - analysis; Chromosome Aberrations; Comet Assay; Deoxyguanosine - analogs & derivatives; Deoxyguanosine - urine; DNA Damage - drug effects; DNA Damage - genetics; Environmental Exposure - adverse effects; Environmental Exposure - analysis; Humans; Micronucleus Tests; Motor Vehicles; Mutagenicity Tests - methods; Mutagens - toxicity; Polycyclic Aromatic Hydrocarbons - toxicity; Polymorphism, Genetic; Sister Chromatid Exchange; South America; Asia; North America; Europe; Africa
• ISSN: 0267-8357; 1464-3804; 1464-3804
• DOI: 10.1093/mutage/get042

Diesel and gasoline emissions, which are the primary components of traffic exhaust, are known or possible human carcinogens, respectively, and working or living near high-traffic roads is associated with various health effects, including cancer. To help understand the mechanistic basis for this obse...