Sheng-Mai-Yin inhibits doxorubicin-induced ferroptosis and cardiotoxicity through regulation of Hmox1

• Published in: Aging (Albany, NY.) Vol. 15; no. 19; pp. 10133 - 10145
• Main Authors: Meng, Peina, Chen, Zhaoyang, Sun, Tianhui, Wu, Lili, Wang, Yifan, Guo, Tianwei, Yang, Jin, Zhu, Jiebin
• Format: Journal Article
• Language: English
• Published: Impact Journals 15.10.2023
• Subjects: Research Paper

Doxorubicin (DOX) is a potent chemotherapeutic drug used for treating various cancers. However, its clinical use is limited due to its severe cardiotoxicity, which often results in high mortality rates. Sheng-Mai-Yin (SMY), a Traditional Chinese medicine (TCM) prescription, has been reported to exer...