Carboxyl-modified polystyrene microplastics induces neurotoxicity by affecting dopamine, glutamate, serotonin, and GABA neurotransmission in Caenorhabditis elegans
Microplastics (MPs) are ubiquitous in various environmental media and have potential toxicity. However, the neurotoxicity of carboxyl-modified polystyrene microplastics (PS-COOH) and their mechanisms remain unclear. In this study, Caenorhabditis elegans was used as a model to examine the neurotoxici...
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Published in | Journal of hazardous materials Vol. 445; p. 130543 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
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Elsevier B.V
05.03.2023
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Abstract | Microplastics (MPs) are ubiquitous in various environmental media and have potential toxicity. However, the neurotoxicity of carboxyl-modified polystyrene microplastics (PS-COOH) and their mechanisms remain unclear. In this study, Caenorhabditis elegans was used as a model to examine the neurotoxicity of polystyrene microplastic (PS) and PS-COOH concentrations ranging from 0.1 to 100 μg/L. Locomotion behavior, neuron development, neurotransmitter level, and neurotransmitter-related gene expression were selected as assessment endpoints. Exposure to low concentrations (1 μg/L) of PS-COOH caused more severe neurotoxicity than exposure to pristine PS. In transgenic nematodes, exposure to PS-COOH at 10–100 μg/L significantly increased the fluorescence intensity of dopaminergic, glutamatergic, serotonergic, and aminobutyric acid (GABA)ergic neurons compared to that of the control. Further studies showed that exposure to 100 μg/L PS-COOH can significantly affect the levels of glutamate, serotonin, dopamine, and GABA in nematodes. Likewise, in the present study, the expression of genes involved in neurotransmission was altered in worms. These results suggest that PS-COOH exerts neurotoxicity by affecting neurotransmission of dopamine, glutamate, serotonin, and GABA. This study provides new insights into the underlying mechanisms and potential risks associated with PS-COOH.
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•The neurotoxicity of PS-COOH is more severe than that of PS in C. elegans.•Exposure to PS-COOH caused damage to neurons in nematodes.•Neurotransmitter levels (dopamine, glutamate, serotonin, and GABA) were altered.•The related gene expression following exposure to PS-COOH was observed.•Abnormal neurotransmission may be involved in neurotoxicity of PS-COOH. |
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AbstractList | Microplastics (MPs) are ubiquitous in various environmental media and have potential toxicity. However, the neurotoxicity of carboxyl-modified polystyrene microplastics (PS-COOH) and their mechanisms remain unclear. In this study, Caenorhabditis elegans was used as a model to examine the neurotoxicity of polystyrene microplastic (PS) and PS-COOH concentrations ranging from 0.1 to 100 μg/L. Locomotion behavior, neuron development, neurotransmitter level, and neurotransmitter-related gene expression were selected as assessment endpoints. Exposure to low concentrations (1 μg/L) of PS-COOH caused more severe neurotoxicity than exposure to pristine PS. In transgenic nematodes, exposure to PS-COOH at 10–100 μg/L significantly increased the fluorescence intensity of dopaminergic, glutamatergic, serotonergic, and aminobutyric acid (GABA)ergic neurons compared to that of the control. Further studies showed that exposure to 100 μg/L PS-COOH can significantly affect the levels of glutamate, serotonin, dopamine, and GABA in nematodes. Likewise, in the present study, the expression of genes involved in neurotransmission was altered in worms. These results suggest that PS-COOH exerts neurotoxicity by affecting neurotransmission of dopamine, glutamate, serotonin, and GABA. This study provides new insights into the underlying mechanisms and potential risks associated with PS-COOH.
[Display omitted]
•The neurotoxicity of PS-COOH is more severe than that of PS in C. elegans.•Exposure to PS-COOH caused damage to neurons in nematodes.•Neurotransmitter levels (dopamine, glutamate, serotonin, and GABA) were altered.•The related gene expression following exposure to PS-COOH was observed.•Abnormal neurotransmission may be involved in neurotoxicity of PS-COOH. Microplastics (MPs) are ubiquitous in various environmental media and have potential toxicity. However, the neurotoxicity of carboxyl-modified polystyrene microplastics (PS-COOH) and their mechanisms remain unclear. In this study, Caenorhabditis elegans was used as a model to examine the neurotoxicity of polystyrene microplastic (PS) and PS-COOH concentrations ranging from 0.1 to 100 μg/L. Locomotion behavior, neuron development, neurotransmitter level, and neurotransmitter-related gene expression were selected as assessment endpoints. Exposure to low concentrations (1 μg/L) of PS-COOH caused more severe neurotoxicity than exposure to pristine PS. In transgenic nematodes, exposure to PS-COOH at 10-100 μg/L significantly increased the fluorescence intensity of dopaminergic, glutamatergic, serotonergic, and aminobutyric acid (GABA)ergic neurons compared to that of the control. Further studies showed that exposure to 100 μg/L PS-COOH can significantly affect the levels of glutamate, serotonin, dopamine, and GABA in nematodes. Likewise, in the present study, the expression of genes involved in neurotransmission was altered in worms. These results suggest that PS-COOH exerts neurotoxicity by affecting neurotransmission of dopamine, glutamate, serotonin, and GABA. This study provides new insights into the underlying mechanisms and potential risks associated with PS-COOH. |
ArticleNumber | 130543 |
Author | Dang, Yao Tan, Shihui Li, Hongyan Xiang, Mingdeng Xie, Dongli Chen, Haibo Yu, Yunjiang Yang, Yue |
Author_xml | – sequence: 1 givenname: Yunjiang surname: Yu fullname: Yu, Yunjiang email: yuyunjiang@scies.org organization: State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, China – sequence: 2 givenname: Dongli surname: Xie fullname: Xie, Dongli organization: State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, China – sequence: 3 givenname: Yue surname: Yang fullname: Yang, Yue organization: Xi 'an Jiaotong University Second Affiliated Hospital, Xi 'an 710004, China – sequence: 4 givenname: Shihui surname: Tan fullname: Tan, Shihui organization: State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, China – sequence: 5 givenname: Hongyan surname: Li fullname: Li, Hongyan organization: State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, China – sequence: 6 givenname: Yao surname: Dang fullname: Dang, Yao organization: State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, China – sequence: 7 givenname: Mingdeng surname: Xiang fullname: Xiang, Mingdeng organization: State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, China – sequence: 8 givenname: Haibo surname: Chen fullname: Chen, Haibo email: chenhaibo@shu.edu.cn organization: Institute for Environmental pollution and health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China |
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Cites_doi | 10.1039/C8EN00412A 10.1016/S0896-6273(00)81199-X 10.7554/eLife.14197 10.1007/s11356-021-13184-2 10.1021/acschemneuro.1c00559 10.1016/j.envpol.2020.116337 10.1016/j.chemosphere.2020.127344 10.1073/pnas.1606615113 10.1016/j.neures.2022.01.005 10.1016/j.scitotenv.2022.155092 10.1016/j.jhazmat.2018.06.017 10.1360/TB-2020-0979 10.1016/j.jhazmat.2020.123005 10.1021/acs.est.0c07121 10.1038/s41598-019-52292-5 10.1126/science.7886454 10.1021/acs.est.6b04140 10.1371/journal.pone.0260803 10.3109/17435390.2012.689884 10.1021/la047960+ 10.1021/acs.est.9b02525 10.3389/fmars.2021.800782 10.1039/D1NR00038A 10.1016/j.jhazmat.2020.122418 10.1016/j.trac.2021.116235 10.1016/j.toxrep.2019.08.001 10.1021/acs.chemrestox.0c00501 10.3390/antiox11020268 10.1016/j.neuro.2019.12.011 10.1016/j.chemosphere.2019.01.021 10.1016/j.jhazmat.2020.125016 10.1016/j.jenvman.2019.02.102 10.1002/jat.4197 10.1021/acs.est.1c04509 10.1016/j.watres.2019.115290 10.1016/j.jhazmat.2018.09.020 10.1016/j.tins.2006.01.002 10.1021/acs.est.7b03732 10.1016/j.jenvman.2019.05.103 10.1016/j.tox.2021.153012 10.1016/j.marpolbul.2019.110660 10.1039/C5NR05914C 10.1002/wdev.233 10.1021/acsomega.0c04830 10.3390/ijms22168917 10.1016/j.marpolbul.2019.01.003 10.1016/j.scitotenv.2017.07.144 10.1002/syn.20746 10.1093/toxsci/kfz191 10.1016/j.marpolbul.2016.11.049 10.1038/srep46687 10.1016/j.ijpddr.2018.10.001 10.1016/j.marpolbul.2020.111278 10.1016/j.jhazmat.2021.126482 10.1016/j.envpol.2022.119141 |
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Keywords | Caenorhabditis elegans Neurotoxicity Neuron damage Carboxyl-modified microplastics Neurotransmission |
Language | English |
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References | Kumar, Joishy, Das, Kalita, Mukherjee, Khan (bib24) 2022; 11 Luo, Shi, Tu, Zhou, Ji, Pan, Xu, Wu, An, Sun, He, Li, Ma, Li (bib33) 2021; 66 Hobert (bib17) 2016; 5 Zhang, Jeong, Lee, Wang, Wang (bib57) 2019; 53 Banerjee, Billey, Shelver (bib2) 2021; 16 Wang, Lu, Guo, Wang, He, Liu, Bian, Sheng (bib49) 2022; 834 Muthubharathi, Balasubramaniam, Mir, Ravichandiran, Balamurugan (bib35) 2021; 12 Bhagat, Nishimura, Shimada (bib3) 2021; 138 Deng, Zhang, Qiao, Bonilla, Yang, Ren, Lemos (bib13) 2018; 357 Li, Hu, Qin, Yin (bib29) 2020; 170 Shi, Sun, Han, Tang, Zhou, Du, Liu (bib45) 2021; 409 Zhang, Ye, Sun, Wang, Tang, Xu, Ji, Sun (bib61) 2022; 304 Chen, Wang, Li, Ma, Yu, Li, Xiang, Chen, Hua, Yu (bib7) 2019; 237 Wang, Xu, Li (bib53) 2019; 363 Bozzi, Borrelli (bib5) 2006; 29 Chen, Guo, Li, Zhou, Cao, Wang, Liu, Xiang, Li, Yu (bib6) 2019; 245 Qu, Wang (bib39) 2019; 703 Chen, Chao, Wu, Lai, Chen, Yoshioka, Hsu, Tsai (bib10) 2021; 22 Han, Jing, Zhang, Zhang, Li, Zhang, Gao, Ning, Li (bib15) 2022; 465 Kang, Jeong, Lee, Cui, Kim, Lee, Kim, Han, Hwang, Lee, Lee (bib20) 2017; 124 Sawin, Ranganathan, Horvitz (bib41) 2000; 26 Schultz, Bart, Lahive, Spurgeon (bib42) 2021; 55 Akinyemi, Miah, Ijomone, Tsatsakis, Soares, Tinkov, Skalny, Venkataramani, Aschner (bib1) 2019; 6 Zhang, Li, Li, Chang, Niu, Wu, Kong, Zhang, Tang, Xue (bib60) 2021; 41 Jorgensen (bib19) 2005 Wang, Liu, Qu, Wang (bib50) 2021; 217 Wang, Liu, Zheng, Wang, Fu, Luo, Li, Wang (bib51) 2020; 150 Sammi, Foguth, Nieves, De Perre, Wipf, McMurray, Lee, Cannon (bib40) 2019; 172 Kim, Chae, An (bib21) 2017; 51 Deng, Zhang, Lemos, Ren (bib12) 2017; 7 Tlili, Jemai, Brinis, Regaya (bib47) 2020; 258 Li, Feng, Wu, Guo (bib28) 2020; 392 Kim, Eom, Choi, Hong, Choi (bib23) 2020; 77 Kim, Nguyen Phuoc, Min, Nguyen Hoang, Kim, Yoon, Kwon (bib22) 2020; 399 Shen, Wen, Liu, Zhong, Qin, Harris, Kawano, Wu, Xu, Samuel, Zhang (bib44) 2016; 5 Wu, Xu, Liang, Tang (bib54) 2019; 221 Foster, Cochrane, Khatami, Habibi, de Haan, Forrester (bib14) 2018; 8 Wu, He, Zhan, Ang, Ying, Zhang, Zhang, Xue, Tang (bib55) 2015; 7 Zhang, Cheng, Wang, Duan, Cui, Shi, Qin (bib58) 2022; 8 Wang (bib48) 2019 Chen, Hua, Yang, Wang, Jin, Dong, Chang, Ding, Xiang, Li, Yu (bib8) 2021; 419 Chen, Yin, Jia, Schiwy, Legradi, Yang, Hollert (bib9) 2017; 609 Nigamatzyanova, Fakhrullin (bib36) 2021; 271 Segalat, Elkes, Kaplan (bib43) 1995; 267 Nizzetto, Futter, Langaas (bib37) 2016; 50 Qiao, Chen, Wang, Bai, Cui, Liu, Wu, Chen (bib38) 2021; 13 Lenz, Enders, Nielsen (bib26) 2016; 113 Yang, Dong, Wu, Wang (bib56) 2021; 34 Luan, Wang, Zheng, Liu, Luo, Li (bib32) 2019; 139 Tian, Baek, Lee, Jang (bib46) 2010; 64 Liu, Chen, Li, Ke, Huang, Bian, Guo, Wu, Han, Liu (bib31) 2020; 5 Zhang, Li (bib59) 2021; 40 Bhattacharya, Khare (bib4) 2020; 38 Li, Yu, Wu, Tang, Wang (bib27) 2013; 7 Hazeem, Yesilay, Bououdina, Perna, Cetin, Suludere, Barras, Boukherroub (bib16) 2020; 156 Limonta, Mancia, Benkhalqui, Bertolucci, Abelli, Fossi, Panti (bib30) 2019; 9 Issac, Kandasubramanian (bib18) 2021; 28 Musyanovych, Adler, Colloids (bib34) 2005; 21 Chou, Chen, Liao, Pan (bib11) 2022; 178 Lei, Liu, Song, Lu, Hu, Cao, Xie, Shi, He (bib25) 2018; 5 Wang, Yang, Liu, Zhao, Liu, Xing (bib52) 2021; 55 Zhang (10.1016/j.jhazmat.2022.130543_bib60) 2021; 41 Sammi (10.1016/j.jhazmat.2022.130543_bib40) 2019; 172 Kumar (10.1016/j.jhazmat.2022.130543_bib24) 2022; 11 Lenz (10.1016/j.jhazmat.2022.130543_bib26) 2016; 113 Li (10.1016/j.jhazmat.2022.130543_bib28) 2020; 392 Bhagat (10.1016/j.jhazmat.2022.130543_bib3) 2021; 138 Kim (10.1016/j.jhazmat.2022.130543_bib21) 2017; 51 Wang (10.1016/j.jhazmat.2022.130543_bib51) 2020; 150 Zhang (10.1016/j.jhazmat.2022.130543_bib59) 2021; 40 Bhattacharya (10.1016/j.jhazmat.2022.130543_bib4) 2020; 38 Wang (10.1016/j.jhazmat.2022.130543_bib48) 2019 Li (10.1016/j.jhazmat.2022.130543_bib29) 2020; 170 Chou (10.1016/j.jhazmat.2022.130543_bib11) 2022; 178 Kim (10.1016/j.jhazmat.2022.130543_bib22) 2020; 399 Shi (10.1016/j.jhazmat.2022.130543_bib45) 2021; 409 Wang (10.1016/j.jhazmat.2022.130543_bib52) 2021; 55 Qiao (10.1016/j.jhazmat.2022.130543_bib38) 2021; 13 Chen (10.1016/j.jhazmat.2022.130543_bib10) 2021; 22 Zhang (10.1016/j.jhazmat.2022.130543_bib58) 2022; 8 Akinyemi (10.1016/j.jhazmat.2022.130543_bib1) 2019; 6 Zhang (10.1016/j.jhazmat.2022.130543_bib57) 2019; 53 Segalat (10.1016/j.jhazmat.2022.130543_bib43) 1995; 267 Li (10.1016/j.jhazmat.2022.130543_bib27) 2013; 7 Han (10.1016/j.jhazmat.2022.130543_bib15) 2022; 465 Issac (10.1016/j.jhazmat.2022.130543_bib18) 2021; 28 Musyanovych (10.1016/j.jhazmat.2022.130543_bib34) 2005; 21 Sawin (10.1016/j.jhazmat.2022.130543_bib41) 2000; 26 Wu (10.1016/j.jhazmat.2022.130543_bib55) 2015; 7 Wang (10.1016/j.jhazmat.2022.130543_bib50) 2021; 217 Yang (10.1016/j.jhazmat.2022.130543_bib56) 2021; 34 Jorgensen (10.1016/j.jhazmat.2022.130543_bib19) 2005 Kang (10.1016/j.jhazmat.2022.130543_bib20) 2017; 124 Luo (10.1016/j.jhazmat.2022.130543_bib33) 2021; 66 Wang (10.1016/j.jhazmat.2022.130543_bib53) 2019; 363 Schultz (10.1016/j.jhazmat.2022.130543_bib42) 2021; 55 Nigamatzyanova (10.1016/j.jhazmat.2022.130543_bib36) 2021; 271 Banerjee (10.1016/j.jhazmat.2022.130543_bib2) 2021; 16 Muthubharathi (10.1016/j.jhazmat.2022.130543_bib35) 2021; 12 Foster (10.1016/j.jhazmat.2022.130543_bib14) 2018; 8 Deng (10.1016/j.jhazmat.2022.130543_bib13) 2018; 357 Nizzetto (10.1016/j.jhazmat.2022.130543_bib37) 2016; 50 Chen (10.1016/j.jhazmat.2022.130543_bib8) 2021; 419 Wu (10.1016/j.jhazmat.2022.130543_bib54) 2019; 221 Hobert (10.1016/j.jhazmat.2022.130543_bib17) 2016; 5 Wang (10.1016/j.jhazmat.2022.130543_bib49) 2022; 834 Deng (10.1016/j.jhazmat.2022.130543_bib12) 2017; 7 Kim (10.1016/j.jhazmat.2022.130543_bib23) 2020; 77 Tlili (10.1016/j.jhazmat.2022.130543_bib47) 2020; 258 Zhang (10.1016/j.jhazmat.2022.130543_bib61) 2022; 304 Qu (10.1016/j.jhazmat.2022.130543_bib39) 2019; 703 Chen (10.1016/j.jhazmat.2022.130543_bib6) 2019; 245 Bozzi (10.1016/j.jhazmat.2022.130543_bib5) 2006; 29 Chen (10.1016/j.jhazmat.2022.130543_bib9) 2017; 609 Liu (10.1016/j.jhazmat.2022.130543_bib31) 2020; 5 Luan (10.1016/j.jhazmat.2022.130543_bib32) 2019; 139 Tian (10.1016/j.jhazmat.2022.130543_bib46) 2010; 64 Lei (10.1016/j.jhazmat.2022.130543_bib25) 2018; 5 Shen (10.1016/j.jhazmat.2022.130543_bib44) 2016; 5 Chen (10.1016/j.jhazmat.2022.130543_bib7) 2019; 237 Hazeem (10.1016/j.jhazmat.2022.130543_bib16) 2020; 156 Limonta (10.1016/j.jhazmat.2022.130543_bib30) 2019; 9 |
References_xml | – volume: 139 start-page: 346 year: 2019 end-page: 354 ident: bib32 article-title: Differential toxicity of functionalized polystyrene microplastics to clams ( publication-title: Mar. Pollut. Bull. contributor: fullname: Li – volume: 399 year: 2020 ident: bib22 article-title: Comprehensive phenotyping and multi-omic profiling in the toxicity assessment of nanopolystyrene with different surface properties publication-title: J. Hazard. Mater. contributor: fullname: Kwon – volume: 66 start-page: 1547 year: 2021 end-page: 1562 ident: bib33 article-title: Research progresses and prospects of microplastics in the environment publication-title: Chin. Sci. Bull. contributor: fullname: Li – volume: 465 year: 2022 ident: bib15 article-title: Effects of lanthanum nitrate on behavioral disorder, neuronal damage and gene expression in different developmental stages of publication-title: Toxicology contributor: fullname: Li – volume: 170 year: 2020 ident: bib29 article-title: Evaluating the effect of different modified microplastics on the availability of polycyclic aromatic hydrocarbons publication-title: Water Res. contributor: fullname: Yin – volume: 703 year: 2019 ident: bib39 article-title: Toxicity comparison between pristine and sulfonate modified nanopolystyrene particles in affecting locomotion behavior, sensory perception, and neuronal development in publication-title: Sci. Total. Environ. contributor: fullname: Wang – volume: 41 start-page: 2055 year: 2021 end-page: 2067 ident: bib60 article-title: Neurobehavior and neuron damage following prolonged exposure of silver nanoparticles with/without polyvinylpyrrolidone coating in publication-title: J. Appl. Toxicol. contributor: fullname: Xue – volume: 245 start-page: 216 year: 2019 end-page: 222 ident: bib6 article-title: Multi-generational effects and variations of stress response by hexabromocyclododecane (HBCD) exposure in the nematode publication-title: J. Environ. Manag. contributor: fullname: Yu – volume: 156 year: 2020 ident: bib16 article-title: Investigation of the toxic effects of different polystyrene micro-and nanoplastics on microalgae publication-title: Mar. Pollut. Bull. contributor: fullname: Boukherroub – volume: 138 year: 2021 ident: bib3 article-title: Worming into a robust model to unravel the micro/nanoplastic toxicity in soil: a review on publication-title: Trac-Trend Anal. Chem. contributor: fullname: Shimada – volume: 8 year: 2022 ident: bib58 article-title: Influence of Functional Group Modification on the Toxicity of Nanoplastics publication-title: Front. Mar. Sci. contributor: fullname: Qin – volume: 7 start-page: 1004 year: 2013 end-page: 1013 ident: bib27 article-title: Transmissions of serotonin, dopamine, and glutamate are required for the formation of neurotoxicity from Al publication-title: Nanotoxicology contributor: fullname: Wang – volume: 363 start-page: 268 year: 2019 end-page: 276 ident: bib53 article-title: Impacts of methamphetamine and ketamine on C.elegans's physiological functions at environmentally relevant concentrations and eco-risk assessment in surface waters publication-title: J. Hazard. Mater. contributor: fullname: Li – volume: 12 start-page: 4336 year: 2021 end-page: 4349 ident: bib35 article-title: Physiological and Metabolite Alterations Associated with Neuronal Signals of publication-title: ACS Chem. Neurosci. contributor: fullname: Balamurugan – volume: 8 start-page: 534 year: 2018 end-page: 539 ident: bib14 article-title: A mutational and molecular dynamics study of the cys-loop GABA receptor Hco-UNC-49 from Haemonchus contortus: Agonist recognition in the nematode GABA receptor family publication-title: Int. J. Parasitol. -Drug contributor: fullname: Forrester – volume: 55 start-page: 6065 year: 2021 end-page: 6075 ident: bib42 article-title: What Is on the outside matters-surface charge and dissolve organic matter association affect the toxicity and physiological mode of action of polystyrene nanoplastics to publication-title: Environ. Sci. Technol. contributor: fullname: Spurgeon – volume: 834 year: 2022 ident: bib49 article-title: Effects of polystyrene nanoplastics with different functional groups on rice ( publication-title: Sci. Total. Environ. contributor: fullname: Sheng – volume: 40 start-page: 28 year: 2021 end-page: 40 ident: bib59 article-title: Review on the occurrence, analysis methods,toxicity and health effects of micro-and nano-plastics in the environment publication-title: Environ. Chem. contributor: fullname: Li – volume: 16 year: 2021 ident: bib2 article-title: Uptake and toxicity of polystyrene micro/nanoplastics in gastric cells: effects of particle size and surface functionalization publication-title: Plos One contributor: fullname: Shelver – volume: 5 start-page: 474 year: 2016 end-page: 498 ident: bib17 article-title: A map of terminal regulators of neuronal identity in publication-title: Wires Dev. Biol. contributor: fullname: Hobert – volume: 124 start-page: 614 year: 2017 end-page: 623 ident: bib20 article-title: Cross-reactivities of mammalian MAPKs antibodies in rotifer and copepod: application in mechanistic studies in aquatic ecotoxicology publication-title: Mar. Pollut. Bull. contributor: fullname: Lee – volume: 7 start-page: 20460 year: 2015 end-page: 20473 ident: bib55 article-title: MPA-capped CdTe quantum dots exposure causes neurotoxic effects in nematode publication-title: Nanoscale contributor: fullname: Tang – volume: 50 start-page: 10777 year: 2016 end-page: 10779 ident: bib37 article-title: Are Agricultural Soils Dumps for Microplastics of Urban Origin? publication-title: Environ. Sci. Technol. contributor: fullname: Langaas – volume: 5 start-page: 2009 year: 2018 end-page: 2020 ident: bib25 article-title: Polystyrene (nano)microplastics cause size-dependent neurotoxicity, oxidative damage and other adverse effects in publication-title: Environ. Sci. -Nano contributor: fullname: He – volume: 178 start-page: 87 year: 2022 end-page: 92 ident: bib11 article-title: A role for dopamine in publication-title: Neurosci. Res contributor: fullname: Pan – volume: 258 year: 2020 ident: bib47 article-title: Microplastics mixture exposure at environmentally relevant conditions induce oxidative stress and neurotoxicity in the wedge clam publication-title: Chemosphere contributor: fullname: Regaya – volume: 357 start-page: 348 year: 2018 end-page: 354 ident: bib13 article-title: Evidence that microplastics aggravate the toxicity of organophosphorus flame retardants in mice ( publication-title: J. Hazard. Mater. contributor: fullname: Lemos – volume: 267 start-page: 1648 year: 1995 end-page: 1651 ident: bib43 article-title: Modulation of serotonin-controlled behaviors by G(O) in publication-title: Science contributor: fullname: Kaplan – volume: 7 start-page: 46687 year: 2017 ident: bib12 article-title: Tissue accumulation of microplastics in mice and biomarker responses suggest widespread health risks of exposure publication-title: Sci. Rep. contributor: fullname: Ren – volume: 13 start-page: 8806 year: 2021 end-page: 8816 ident: bib38 article-title: Perturbation of gut microbiota plays an important role in micro/nanoplastics-induced gut barrier dysfunction publication-title: Nanoscale contributor: fullname: Chen – volume: 609 start-page: 1312 year: 2017 end-page: 1321 ident: bib9 article-title: Enhanced uptake of BPA in the presence of nanoplastics can lead to neurotoxic effects in adult zebrafish publication-title: Sci. Total Environ. contributor: fullname: Hollert – volume: 5 year: 2016 ident: bib44 article-title: An extrasynaptic GABAergic signal modulates a pattern of forward movement in publication-title: eLife contributor: fullname: Zhang – volume: 53 start-page: 8426 year: 2019 end-page: 8436 ident: bib57 article-title: Transgenerational Proteome Plasticity in Resilience of a Marine Copepod in Response to Environmentally Relevant Concentrations of Microplastics publication-title: Environ. Sci. Technol. contributor: fullname: Wang – volume: 172 start-page: 417 year: 2019 end-page: 434 ident: bib40 article-title: Perfluorooctane Sulfonate (PFOS) Produces Dopaminergic Neuropathology in publication-title: Toxicol. Sci. contributor: fullname: Cannon – volume: 64 start-page: 432 year: 2010 end-page: 439 ident: bib46 article-title: Prenatal and postnatal exposure to bisphenol a induces anxiolytic behaviors and cognitive deficits in mice publication-title: Synapse contributor: fullname: Jang – volume: 5 start-page: 33170 year: 2020 end-page: 33177 ident: bib31 article-title: Neurodevelopmental Toxicity of Polystyrene Nanoplastics in publication-title: ACS Omega contributor: fullname: Liu – volume: 304 year: 2022 ident: bib61 article-title: Abnormal neurotransmission of GABA and serotonin in publication-title: Environ. Pollut. contributor: fullname: Sun – volume: 237 start-page: 519 year: 2019 end-page: 525 ident: bib7 article-title: A review of toxicity induced by persistent organic pollutants (POPs) and endocrine-disrupting chemicals (EDCs) in the nematode publication-title: J. Environ. Manag. contributor: fullname: Yu – volume: 11 start-page: 268 year: 2022 ident: bib24 article-title: A Potential Probiotic Lactobacillus plantarum JBC5 Improves Longevity and Healthy Aging by Modulating Antioxidative, Innate Immunity and Serotonin-Signaling Pathways in publication-title: Antioxidants contributor: fullname: Khan – year: 2019 ident: bib48 article-title: Target Organ Toxicology in Caenorhabditis Elegans contributor: fullname: Wang – start-page: 1 year: 2005 end-page: 13 ident: bib19 article-title: Gaba publication-title: WormBook contributor: fullname: Jorgensen – volume: 51 start-page: 12852 year: 2017 end-page: 12858 ident: bib21 article-title: Mixture toxicity of nickel and microplastics with different functional groups on publication-title: Environ. Sci. Technol. contributor: fullname: An – volume: 113 start-page: E4121 year: 2016 end-page: E4122 ident: bib26 article-title: Microplastic exposure studies should be environmentally realistic publication-title: Proc. Natl. Acad. Sci. Usa. contributor: fullname: Nielsen – volume: 150 year: 2020 ident: bib51 article-title: Polystyrene microplastics impaired the feeding and swimming behavior of mysid shrimp publication-title: Mar. Pollut. Bull. contributor: fullname: Wang – volume: 38 start-page: 1 year: 2020 end-page: 20 ident: bib4 article-title: Ecological and toxicological manifestations of microplastics: current scenario, research gaps, and possible alleviation measures publication-title: J. Environ. Sci. Heal. C. -Tox contributor: fullname: Khare – volume: 419 year: 2021 ident: bib8 article-title: Chronic exposure to UV-aged microplastics induces neurotoxicity by affecting dopamine, glutamate, and serotonin neurotransmission in publication-title: J. Hazard. Mater. contributor: fullname: Yu – volume: 9 start-page: 15775 year: 2019 ident: bib30 article-title: Microplastics induce transcriptional changes, immune response and behavioral alterations in adult zebrafish publication-title: Sci. Rep. contributor: fullname: Panti – volume: 6 start-page: 833 year: 2019 end-page: 840 ident: bib1 article-title: Lead (Pb) exposure induces dopaminergic neurotoxicity in publication-title: Toxicol. Rep. contributor: fullname: Aschner – volume: 29 start-page: 167 year: 2006 end-page: 174 ident: bib5 article-title: Dopamine in neurotoxicity and neuroprotection: what do D-2 receptors have to do with it? publication-title: Trends Neurosci. contributor: fullname: Borrelli – volume: 21 start-page: 2209 year: 2005 end-page: 2217 ident: bib34 article-title: Grafting of amino functional monomer onto initiator-modified polystyrene particles publication-title: Langmuir contributor: fullname: Colloids – volume: 217 year: 2021 ident: bib50 article-title: Response of tyramine and glutamate related signals to nanoplastic exposure in publication-title: Safe contributor: fullname: Wang – volume: 409 year: 2021 ident: bib45 article-title: Microplastics impair olfactory-mediated behaviors of goldfish publication-title: J. Hazard. Mater. contributor: fullname: Liu – volume: 22 start-page: 8917 year: 2021 ident: bib10 article-title: Effect of 9,12-octadecadiynoic acid on neurobehavioral development in publication-title: Int. J. Mol. Sci. contributor: fullname: Tsai – volume: 392 year: 2020 ident: bib28 article-title: Impacts of nanoplastics on bivalve: Fluorescence tracing of organ accumulation, oxidative stress and damage publication-title: J. Hazard. Mater. contributor: fullname: Guo – volume: 26 start-page: 619 year: 2000 end-page: 631 ident: bib41 article-title: locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway publication-title: Neuron contributor: fullname: Horvitz – volume: 34 start-page: 1308 year: 2021 end-page: 1318 ident: bib56 article-title: Induction of Protective Response Associated with Expressional Alterations in Neuronal G Protein-Coupled Receptors in Polystyrene Nanoparticle Exposed publication-title: Chem. Res. Toxicol. contributor: fullname: Wang – volume: 271 year: 2021 ident: bib36 article-title: Dark-field hyperspectral microscopy for label-free microplastics and nanoplastics detection and identification in vivo: A publication-title: Environ. Pollut. contributor: fullname: Fakhrullin – volume: 55 start-page: 15579 year: 2021 end-page: 15595 ident: bib52 article-title: Interaction of Microplastics with Antibiotics in Aquatic Environment: Distribution, Adsorption, and Toxicity publication-title: Environ. Sci. Technol. contributor: fullname: Xing – volume: 28 start-page: 19544 year: 2021 end-page: 19562 ident: bib18 article-title: Effect of microplastics in water and aquatic systems publication-title: Environ. Sci. Pollut. Res. contributor: fullname: Kandasubramanian – volume: 221 start-page: 708 year: 2019 end-page: 726 ident: bib54 article-title: as a complete model organism for biosafety assessments of nanoparticles publication-title: Chemosphere contributor: fullname: Tang – volume: 77 start-page: 30 year: 2020 end-page: 39 ident: bib23 article-title: Graphene oxide-induced neurotoxicity on neurotransmitters, AFD neurons and locomotive behavior in publication-title: Neurotoxicology contributor: fullname: Choi – volume: 5 start-page: 2009 year: 2018 ident: 10.1016/j.jhazmat.2022.130543_bib25 article-title: Polystyrene (nano)microplastics cause size-dependent neurotoxicity, oxidative damage and other adverse effects in Caenorhabditis elegans publication-title: Environ. Sci. -Nano doi: 10.1039/C8EN00412A contributor: fullname: Lei – volume: 26 start-page: 619 year: 2000 ident: 10.1016/j.jhazmat.2022.130543_bib41 article-title: C-elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway publication-title: Neuron doi: 10.1016/S0896-6273(00)81199-X contributor: fullname: Sawin – volume: 5 year: 2016 ident: 10.1016/j.jhazmat.2022.130543_bib44 article-title: An extrasynaptic GABAergic signal modulates a pattern of forward movement in Caenorhabditis elegans publication-title: eLife doi: 10.7554/eLife.14197 contributor: fullname: Shen – volume: 28 start-page: 19544 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib18 article-title: Effect of microplastics in water and aquatic systems publication-title: Environ. Sci. Pollut. Res. doi: 10.1007/s11356-021-13184-2 contributor: fullname: Issac – volume: 12 start-page: 4336 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib35 article-title: Physiological and Metabolite Alterations Associated with Neuronal Signals of Caenorhabditis elegans during Cronobacter sakazakii Infections publication-title: ACS Chem. Neurosci. doi: 10.1021/acschemneuro.1c00559 contributor: fullname: Muthubharathi – volume: 271 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib36 article-title: Dark-field hyperspectral microscopy for label-free microplastics and nanoplastics detection and identification in vivo: A Caenorhabditis elegans study publication-title: Environ. Pollut. doi: 10.1016/j.envpol.2020.116337 contributor: fullname: Nigamatzyanova – volume: 258 year: 2020 ident: 10.1016/j.jhazmat.2022.130543_bib47 article-title: Microplastics mixture exposure at environmentally relevant conditions induce oxidative stress and neurotoxicity in the wedge clam Donax trunculus publication-title: Chemosphere doi: 10.1016/j.chemosphere.2020.127344 contributor: fullname: Tlili – volume: 113 start-page: E4121 year: 2016 ident: 10.1016/j.jhazmat.2022.130543_bib26 article-title: Microplastic exposure studies should be environmentally realistic publication-title: Proc. Natl. Acad. Sci. Usa. doi: 10.1073/pnas.1606615113 contributor: fullname: Lenz – volume: 178 start-page: 87 year: 2022 ident: 10.1016/j.jhazmat.2022.130543_bib11 article-title: A role for dopamine in C. elegans avoidance behavior induced by mitochondrial stress publication-title: Neurosci. Res doi: 10.1016/j.neures.2022.01.005 contributor: fullname: Chou – volume: 834 year: 2022 ident: 10.1016/j.jhazmat.2022.130543_bib49 article-title: Effects of polystyrene nanoplastics with different functional groups on rice (Oryza sativa L.) seedlings: Combined transcriptome, enzymology, and physiology publication-title: Sci. Total. Environ. doi: 10.1016/j.scitotenv.2022.155092 contributor: fullname: Wang – volume: 357 start-page: 348 year: 2018 ident: 10.1016/j.jhazmat.2022.130543_bib13 article-title: Evidence that microplastics aggravate the toxicity of organophosphorus flame retardants in mice (Mus musculus) publication-title: J. Hazard. Mater. doi: 10.1016/j.jhazmat.2018.06.017 contributor: fullname: Deng – volume: 66 start-page: 1547 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib33 article-title: Research progresses and prospects of microplastics in the environment publication-title: Chin. Sci. Bull. doi: 10.1360/TB-2020-0979 contributor: fullname: Luo – volume: 399 year: 2020 ident: 10.1016/j.jhazmat.2022.130543_bib22 article-title: Comprehensive phenotyping and multi-omic profiling in the toxicity assessment of nanopolystyrene with different surface properties publication-title: J. Hazard. Mater. doi: 10.1016/j.jhazmat.2020.123005 contributor: fullname: Kim – volume: 55 start-page: 6065 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib42 article-title: What Is on the outside matters-surface charge and dissolve organic matter association affect the toxicity and physiological mode of action of polystyrene nanoplastics to C. elegans publication-title: Environ. Sci. Technol. doi: 10.1021/acs.est.0c07121 contributor: fullname: Schultz – volume: 9 start-page: 15775 year: 2019 ident: 10.1016/j.jhazmat.2022.130543_bib30 article-title: Microplastics induce transcriptional changes, immune response and behavioral alterations in adult zebrafish publication-title: Sci. Rep. doi: 10.1038/s41598-019-52292-5 contributor: fullname: Limonta – volume: 267 start-page: 1648 year: 1995 ident: 10.1016/j.jhazmat.2022.130543_bib43 article-title: Modulation of serotonin-controlled behaviors by G(O) in Caenorhabditis-Elegans publication-title: Science doi: 10.1126/science.7886454 contributor: fullname: Segalat – volume: 50 start-page: 10777 year: 2016 ident: 10.1016/j.jhazmat.2022.130543_bib37 article-title: Are Agricultural Soils Dumps for Microplastics of Urban Origin? publication-title: Environ. Sci. Technol. doi: 10.1021/acs.est.6b04140 contributor: fullname: Nizzetto – volume: 16 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib2 article-title: Uptake and toxicity of polystyrene micro/nanoplastics in gastric cells: effects of particle size and surface functionalization publication-title: Plos One doi: 10.1371/journal.pone.0260803 contributor: fullname: Banerjee – volume: 7 start-page: 1004 year: 2013 ident: 10.1016/j.jhazmat.2022.130543_bib27 article-title: Transmissions of serotonin, dopamine, and glutamate are required for the formation of neurotoxicity from Al2O3-NPs in nematode Caenorhabditis elegans publication-title: Nanotoxicology doi: 10.3109/17435390.2012.689884 contributor: fullname: Li – volume: 21 start-page: 2209 year: 2005 ident: 10.1016/j.jhazmat.2022.130543_bib34 article-title: Grafting of amino functional monomer onto initiator-modified polystyrene particles publication-title: Langmuir doi: 10.1021/la047960+ contributor: fullname: Musyanovych – volume: 53 start-page: 8426 year: 2019 ident: 10.1016/j.jhazmat.2022.130543_bib57 article-title: Transgenerational Proteome Plasticity in Resilience of a Marine Copepod in Response to Environmentally Relevant Concentrations of Microplastics publication-title: Environ. Sci. Technol. doi: 10.1021/acs.est.9b02525 contributor: fullname: Zhang – volume: 8 year: 2022 ident: 10.1016/j.jhazmat.2022.130543_bib58 article-title: Influence of Functional Group Modification on the Toxicity of Nanoplastics publication-title: Front. Mar. Sci. doi: 10.3389/fmars.2021.800782 contributor: fullname: Zhang – volume: 13 start-page: 8806 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib38 article-title: Perturbation of gut microbiota plays an important role in micro/nanoplastics-induced gut barrier dysfunction publication-title: Nanoscale doi: 10.1039/D1NR00038A contributor: fullname: Qiao – volume: 392 year: 2020 ident: 10.1016/j.jhazmat.2022.130543_bib28 article-title: Impacts of nanoplastics on bivalve: Fluorescence tracing of organ accumulation, oxidative stress and damage publication-title: J. Hazard. Mater. doi: 10.1016/j.jhazmat.2020.122418 contributor: fullname: Li – volume: 138 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib3 article-title: Worming into a robust model to unravel the micro/nanoplastic toxicity in soil: a review on Caenorhabditis elegans publication-title: Trac-Trend Anal. Chem. doi: 10.1016/j.trac.2021.116235 contributor: fullname: Bhagat – volume: 6 start-page: 833 year: 2019 ident: 10.1016/j.jhazmat.2022.130543_bib1 article-title: Lead (Pb) exposure induces dopaminergic neurotoxicity in Caenorhabditis elegans: involvement of the dopamine transporter publication-title: Toxicol. Rep. doi: 10.1016/j.toxrep.2019.08.001 contributor: fullname: Akinyemi – volume: 34 start-page: 1308 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib56 article-title: Induction of Protective Response Associated with Expressional Alterations in Neuronal G Protein-Coupled Receptors in Polystyrene Nanoparticle Exposed Caenorhabditis elegans publication-title: Chem. Res. Toxicol. doi: 10.1021/acs.chemrestox.0c00501 contributor: fullname: Yang – volume: 11 start-page: 268 year: 2022 ident: 10.1016/j.jhazmat.2022.130543_bib24 article-title: A Potential Probiotic Lactobacillus plantarum JBC5 Improves Longevity and Healthy Aging by Modulating Antioxidative, Innate Immunity and Serotonin-Signaling Pathways in Caenorhabditis elegans publication-title: Antioxidants doi: 10.3390/antiox11020268 contributor: fullname: Kumar – volume: 77 start-page: 30 year: 2020 ident: 10.1016/j.jhazmat.2022.130543_bib23 article-title: Graphene oxide-induced neurotoxicity on neurotransmitters, AFD neurons and locomotive behavior in Caenorhabditis elegans publication-title: Neurotoxicology doi: 10.1016/j.neuro.2019.12.011 contributor: fullname: Kim – volume: 221 start-page: 708 year: 2019 ident: 10.1016/j.jhazmat.2022.130543_bib54 article-title: Caenorhabditis elegans as a complete model organism for biosafety assessments of nanoparticles publication-title: Chemosphere doi: 10.1016/j.chemosphere.2019.01.021 contributor: fullname: Wu – volume: 409 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib45 article-title: Microplastics impair olfactory-mediated behaviors of goldfish Carassius auratus publication-title: J. Hazard. Mater. doi: 10.1016/j.jhazmat.2020.125016 contributor: fullname: Shi – volume: 237 start-page: 519 year: 2019 ident: 10.1016/j.jhazmat.2022.130543_bib7 article-title: A review of toxicity induced by persistent organic pollutants (POPs) and endocrine-disrupting chemicals (EDCs) in the nematode Caenorhabditis elegans publication-title: J. Environ. Manag. doi: 10.1016/j.jenvman.2019.02.102 contributor: fullname: Chen – volume: 41 start-page: 2055 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib60 article-title: Neurobehavior and neuron damage following prolonged exposure of silver nanoparticles with/without polyvinylpyrrolidone coating in Caenorhabditis elegans publication-title: J. Appl. Toxicol. doi: 10.1002/jat.4197 contributor: fullname: Zhang – volume: 55 start-page: 15579 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib52 article-title: Interaction of Microplastics with Antibiotics in Aquatic Environment: Distribution, Adsorption, and Toxicity publication-title: Environ. Sci. Technol. doi: 10.1021/acs.est.1c04509 contributor: fullname: Wang – volume: 170 year: 2020 ident: 10.1016/j.jhazmat.2022.130543_bib29 article-title: Evaluating the effect of different modified microplastics on the availability of polycyclic aromatic hydrocarbons publication-title: Water Res. doi: 10.1016/j.watres.2019.115290 contributor: fullname: Li – volume: 363 start-page: 268 year: 2019 ident: 10.1016/j.jhazmat.2022.130543_bib53 article-title: Impacts of methamphetamine and ketamine on C.elegans's physiological functions at environmentally relevant concentrations and eco-risk assessment in surface waters publication-title: J. Hazard. Mater. doi: 10.1016/j.jhazmat.2018.09.020 contributor: fullname: Wang – volume: 29 start-page: 167 year: 2006 ident: 10.1016/j.jhazmat.2022.130543_bib5 article-title: Dopamine in neurotoxicity and neuroprotection: what do D-2 receptors have to do with it? publication-title: Trends Neurosci. doi: 10.1016/j.tins.2006.01.002 contributor: fullname: Bozzi – volume: 51 start-page: 12852 year: 2017 ident: 10.1016/j.jhazmat.2022.130543_bib21 article-title: Mixture toxicity of nickel and microplastics with different functional groups on Daphnia magna publication-title: Environ. Sci. Technol. doi: 10.1021/acs.est.7b03732 contributor: fullname: Kim – volume: 245 start-page: 216 year: 2019 ident: 10.1016/j.jhazmat.2022.130543_bib6 article-title: Multi-generational effects and variations of stress response by hexabromocyclododecane (HBCD) exposure in the nematode Caenorhabditis elegans publication-title: J. Environ. Manag. doi: 10.1016/j.jenvman.2019.05.103 contributor: fullname: Chen – volume: 465 year: 2022 ident: 10.1016/j.jhazmat.2022.130543_bib15 article-title: Effects of lanthanum nitrate on behavioral disorder, neuronal damage and gene expression in different developmental stages of Caenorhabditis elegans publication-title: Toxicology doi: 10.1016/j.tox.2021.153012 contributor: fullname: Han – volume: 150 year: 2020 ident: 10.1016/j.jhazmat.2022.130543_bib51 article-title: Polystyrene microplastics impaired the feeding and swimming behavior of mysid shrimp Neomysis japonica publication-title: Mar. Pollut. Bull. doi: 10.1016/j.marpolbul.2019.110660 contributor: fullname: Wang – volume: 7 start-page: 20460 year: 2015 ident: 10.1016/j.jhazmat.2022.130543_bib55 article-title: MPA-capped CdTe quantum dots exposure causes neurotoxic effects in nematode Caenorhabditis elegans by affecting the transporters and receptors of glutamate, serotonin and dopamine at the genetic level, or by increasing ROS, or both publication-title: Nanoscale doi: 10.1039/C5NR05914C contributor: fullname: Wu – volume: 5 start-page: 474 year: 2016 ident: 10.1016/j.jhazmat.2022.130543_bib17 article-title: A map of terminal regulators of neuronal identity in Caenorhabditis elegans publication-title: Wires Dev. Biol. doi: 10.1002/wdev.233 contributor: fullname: Hobert – volume: 38 start-page: 1 year: 2020 ident: 10.1016/j.jhazmat.2022.130543_bib4 article-title: Ecological and toxicological manifestations of microplastics: current scenario, research gaps, and possible alleviation measures publication-title: J. Environ. Sci. Heal. C. -Tox contributor: fullname: Bhattacharya – volume: 5 start-page: 33170 year: 2020 ident: 10.1016/j.jhazmat.2022.130543_bib31 article-title: Neurodevelopmental Toxicity of Polystyrene Nanoplastics in Caenorhabditis elegans and the Regulating Effect of Presenilin publication-title: ACS Omega doi: 10.1021/acsomega.0c04830 contributor: fullname: Liu – volume: 22 start-page: 8917 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib10 article-title: Effect of 9,12-octadecadiynoic acid on neurobehavioral development in Caenorhabditis elegans publication-title: Int. J. Mol. Sci. doi: 10.3390/ijms22168917 contributor: fullname: Chen – volume: 139 start-page: 346 year: 2019 ident: 10.1016/j.jhazmat.2022.130543_bib32 article-title: Differential toxicity of functionalized polystyrene microplastics to clams (Meretrix meretrix) at three key development stages of life history publication-title: Mar. Pollut. Bull. doi: 10.1016/j.marpolbul.2019.01.003 contributor: fullname: Luan – volume: 609 start-page: 1312 year: 2017 ident: 10.1016/j.jhazmat.2022.130543_bib9 article-title: Enhanced uptake of BPA in the presence of nanoplastics can lead to neurotoxic effects in adult zebrafish publication-title: Sci. Total Environ. doi: 10.1016/j.scitotenv.2017.07.144 contributor: fullname: Chen – volume: 64 start-page: 432 year: 2010 ident: 10.1016/j.jhazmat.2022.130543_bib46 article-title: Prenatal and postnatal exposure to bisphenol a induces anxiolytic behaviors and cognitive deficits in mice publication-title: Synapse doi: 10.1002/syn.20746 contributor: fullname: Tian – volume: 172 start-page: 417 year: 2019 ident: 10.1016/j.jhazmat.2022.130543_bib40 article-title: Perfluorooctane Sulfonate (PFOS) Produces Dopaminergic Neuropathology in Caenorhabditis elegans publication-title: Toxicol. Sci. doi: 10.1093/toxsci/kfz191 contributor: fullname: Sammi – volume: 124 start-page: 614 year: 2017 ident: 10.1016/j.jhazmat.2022.130543_bib20 article-title: Cross-reactivities of mammalian MAPKs antibodies in rotifer and copepod: application in mechanistic studies in aquatic ecotoxicology publication-title: Mar. Pollut. Bull. doi: 10.1016/j.marpolbul.2016.11.049 contributor: fullname: Kang – volume: 217 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib50 article-title: Response of tyramine and glutamate related signals to nanoplastic exposure in Caenorhabditis elegans. Ecotox. Environ publication-title: Safe contributor: fullname: Wang – year: 2019 ident: 10.1016/j.jhazmat.2022.130543_bib48 contributor: fullname: Wang – volume: 7 start-page: 46687 year: 2017 ident: 10.1016/j.jhazmat.2022.130543_bib12 article-title: Tissue accumulation of microplastics in mice and biomarker responses suggest widespread health risks of exposure publication-title: Sci. Rep. doi: 10.1038/srep46687 contributor: fullname: Deng – volume: 8 start-page: 534 year: 2018 ident: 10.1016/j.jhazmat.2022.130543_bib14 article-title: A mutational and molecular dynamics study of the cys-loop GABA receptor Hco-UNC-49 from Haemonchus contortus: Agonist recognition in the nematode GABA receptor family publication-title: Int. J. Parasitol. -Drug doi: 10.1016/j.ijpddr.2018.10.001 contributor: fullname: Foster – volume: 156 year: 2020 ident: 10.1016/j.jhazmat.2022.130543_bib16 article-title: Investigation of the toxic effects of different polystyrene micro-and nanoplastics on microalgae Chlorella vulgaris by analysis of cell viability, pigment content, oxidative stress and ultrastructural changes publication-title: Mar. Pollut. Bull. doi: 10.1016/j.marpolbul.2020.111278 contributor: fullname: Hazeem – volume: 703 year: 2019 ident: 10.1016/j.jhazmat.2022.130543_bib39 article-title: Toxicity comparison between pristine and sulfonate modified nanopolystyrene particles in affecting locomotion behavior, sensory perception, and neuronal development in Caenorhabditis elegans publication-title: Sci. Total. Environ. contributor: fullname: Qu – volume: 419 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib8 article-title: Chronic exposure to UV-aged microplastics induces neurotoxicity by affecting dopamine, glutamate, and serotonin neurotransmission in Caenorhabditis elegans publication-title: J. Hazard. Mater. doi: 10.1016/j.jhazmat.2021.126482 contributor: fullname: Chen – volume: 304 year: 2022 ident: 10.1016/j.jhazmat.2022.130543_bib61 article-title: Abnormal neurotransmission of GABA and serotonin in Caenorhabditis elegans induced by Fumonisin B1 publication-title: Environ. Pollut. doi: 10.1016/j.envpol.2022.119141 contributor: fullname: Zhang – volume: 40 start-page: 28 year: 2021 ident: 10.1016/j.jhazmat.2022.130543_bib59 article-title: Review on the occurrence, analysis methods,toxicity and health effects of micro-and nano-plastics in the environment publication-title: Environ. Chem. contributor: fullname: Zhang – start-page: 1 year: 2005 ident: 10.1016/j.jhazmat.2022.130543_bib19 article-title: Gaba publication-title: WormBook contributor: fullname: Jorgensen |
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Snippet | Microplastics (MPs) are ubiquitous in various environmental media and have potential toxicity. However, the neurotoxicity of carboxyl-modified polystyrene... |
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SubjectTerms | Animals Caenorhabditis elegans Caenorhabditis elegans - metabolism Carboxyl-modified microplastics Dopamine gamma-Aminobutyric Acid - metabolism Glutamic Acid Microplastics - metabolism Microplastics - toxicity Neuron damage Neurotoxicity Neurotoxicity Syndromes Neurotransmission Neurotransmitter Agents - metabolism Plastics - metabolism Polystyrenes - metabolism Polystyrenes - toxicity Serotonin - metabolism Synaptic Transmission |
Title | Carboxyl-modified polystyrene microplastics induces neurotoxicity by affecting dopamine, glutamate, serotonin, and GABA neurotransmission in Caenorhabditis elegans |
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