Enhanced skin delivery of quercetin by microemulsion

• Published in: Journal of pharmacy and pharmacology Vol. 61; no. 7; p. 855
• Main Authors: Kitagawa, Shuji, Tanaka, Yuko, Tanaka, Manami, Endo, Kanako, Yoshii, Akiko
• Format: Journal Article
• Language: English
• Published: England 01.07.2009
• Subjects: Administration, Cutaneous; Animals; Antioxidants - administration & dosage; Antioxidants - pharmacokinetics; Drug Delivery Systems; Emulsions; Guinea Pigs; In Vitro Techniques; Lipid Peroxidation; Male; Permeability; Quercetin - administration & dosage; Quercetin - pharmacokinetics; Skin - metabolism; Skin Absorption; Solubility; Swine; Swine, Miniature

For topical application of quercetin it is necessary to improve the low efficiency of its intradermal delivery as well as its low solubility in aqueous and organic vesicles. The aim of this study was to determine the usefulness of a microemulsion for that purpose. A microemulsion consisting of isopr...