Synaptic plasticity and the role of astrocytes in central metabolic circuits

• Published in: Wiley interdisciplinary reviews. Mechanisms of disease Vol. 16; no. 1; p. e1632
• Main Authors: Ameroso, Dominique, Rios, Maribel
• Format: Journal Article
• Language: English
• Published: United States 01.01.2024
• Subjects: Animals; Astrocytes - metabolism; Central Nervous System - metabolism; Hypothalamus - metabolism; Neuronal Plasticity - physiology; Obesity - metabolism; Synapses - metabolism; homeostasis; glucose; energy balance; astrocytes; synaptic plasticity; hypothalamus

Neural circuits in the brain, primarily in the hypothalamus, are paramount to the homeostatic control of feeding and energy utilization. They integrate hunger, satiety, and body adiposity cues from the periphery and mediate the appropriate behavioral and physiological responses to satisfy the energy...