Predominance of serotype V and frequency of erythromycin resistance in Streptococcus agalactiae in Ohio

• Published in: American journal of obstetrics and gynecology Vol. 188; no. 5; pp. 1148 - 1150
• Main Authors: Croak, Andrew, Abate, George, Goodrum, Kenneth, Modrzakowski, Malcolm
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA Mosby, Inc 01.05.2003; Elsevier
• Subjects: Anti-Bacterial Agents - pharmacology; antibiotic; Biological and medical sciences; Clindamycin - pharmacology; Drug Resistance; Epidemiology. Vaccinations; Erythromycin - pharmacology; Female; General aspects; Group B Streptococcus; Humans; Infectious diseases; Medical sciences; Ohio; Pregnancy; resistance; sensitivity; serotype V; Serotyping; Streptococcus agalactiae - classification; Streptococcus agalactiae - drug effects; Streptococcus agalactiae - isolation & purification; Vagina - microbiology; Ohio; antibiotic; serotype V; sensitivity; Group B Streptococcus; resistance; Human; Treatment resistance; Prevalence; Drug susceptibility test; Vagina; Erythromycin; Epidemiology; Bacteriological investigation; Macrolide; Streptococcaceae; Antibiotic; Microbiological investigation; Streptococcus B; Bacteria; Micrococcales; Female; Serotype; Antibacterial agent
• ISSN: 0002-9378; 1097-6868
• DOI: 10.1067/mob.2003.293

Objective: The purpose of this study was to test the serotype distribution and antibiotic sensitivity patterns of group B Streptococcus from three Ohio regions in comparison to other areas of the United States. Study Design: Three hundred forty-nine group B Streptococcus isolates from three Ohio hospitals were serotyped specifically, and disk diffusion was used to determine antibiotic susceptibility. Results: Serotype V was isolated most frequently (27%); major types Ia, Ib, II, and III had frequencies of 18%, 9%, 11%, and 17%, respectively. Erythromycin and clindamycin resistance was 12% (n = 200 isolates) and 8% (n = 49 isolates), respectively. Conclusion: The prevalence shift of resistant serotype V group B streptococci in Ohio reflects regional increases and suggests that alternative therapies for patients who are allergic to penicillin may be inadequate. (Am J Obstet Gynecol 2003;188:1148-50.)