A Systematic Review of the Efficacy and Toxicity of Brachytherapy Boost Combined with External Beam Radiotherapy for Nonmetastatic Prostate Cancer

• Published in: European urology oncology Vol. 7; no. 4; pp. 677 - 696
• Main Authors: Slevin, Finbar, Zattoni, Fabio, Checcucci, Enrico, Cumberbatch, Marcus G.K., Nacchia, Antonio, Cornford, Philip, Briers, Erik, De Meerleer, Gert, De Santis, Maria, Eberli, Daniel, Gandaglia, Giorgio, Gillessen, Silke, Grivas, Nikolaos, Liew, Matthew, Linares Espinós, Estefania E., Oldenburg, Jan, Oprea-Lager, Daniela E., Ploussard, Guillaume, Rouvière, Olivier, Schoots, Ivo G., Smith, Emma Jane, Stranne, Johan, Tilki, Derya, Smith, Catrin Tudur, Van Den Bergh, Roderick C.N., Van Oort, Inge M., Wiegel, Thomas, Yuan, Cathy Y., Van den Broeck, Thomas, Henry, Ann M.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.08.2024
• Subjects: Brachytherapy; Brachytherapy boost; Cancer and Oncology; Cancer och onkologi; External beam radiotherapy; Prostate cancer; Urologi och njurmedicin; Urology and Nephrology; Brachytherapy; Brachytherapy boost; External beam radiotherapy; Prostate cancer

There is good evidence that brachytherapy boost combined with external beam radiotherapy improves biochemical control compared with external beam radiotherapy but at the risk of worse urinary toxicity, and its impact on metastatic control and survival is less clear. The optimum use of brachytherapy...