Hypertension-associated changes in retinal blood vessel walls measured in vivo with polarization-sensitive optical coherence tomography

• Published in: Optics and lasers in engineering Vol. 172; p. 107838
• Main Authors: Afsharan, Hadi, Anilkumar, Vidyalakshmi, Silva, Dilusha, Dwivedi, Girish, Joo, Chulmin, Cense, Barry
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.01.2024
• Subjects: Birefringence; Hypertension; Ocular biomechanics; Polarization-sensitive optical coherence tomography; Retinal blood vessel walls; Hypertension; Birefringence; Polarization-sensitive optical coherence tomography; Ocular biomechanics; Retinal blood vessel walls

•PS-OCT can detect abnormalities in the blood vessel wall associated with hypertension.•A new metric termed blood vessel birefringence index (BBI) is introduced.•BBI is able to distinguish between hypertensive and normotensive subjects.•PS-OCT-based BBI indicates high sensitivity and specificity whe...